nocturnal enuresis/dopamine

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[Relationship between dopamine D4 receptor gene polymorphisms and primary nocturnal enuresis].

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OBJECTIVE To study polymorphisms of dopamine D4 receptor (DRD4) in children with primary nocturnal enuresis (PNE) and explore the relationship between DRD4 gene polymorphisms and PNE. METHODS Genomic DNA was isolated from leukocytes in 86 unrelated children with PNE and in 100 healthy unrelated

Linkage study of a large Danish 4-generation family with urge incontinence and nocturnal enuresis.

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OBJECTIVE We studied a large 4-generation family in which night and day voiding problems segregated in an autosomal dominant pattern with a high penetrance. We mapped the gene(s) causing these forms of incontinence using a total genome scan approach. METHODS The family comprises 74 subjects in 4

Desmopressin and vasopressin increase locomotor activity in the rat via a central mechanism: implications for nocturnal enuresis.

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OBJECTIVE Nocturnal enuresis is characterized by nocturnal urine volumes exceeding bladder capacity and by inability to wake up to the stimulus of a full bladder. Desmopressin (DDAVP) is believed to be efficient in treating nocturnal enuresis by reducing nocturnal urine production. However, clinical

Effect of DRD4 receptor -616 C/G polymorphism on brain structure and functional connectivity density in pediatric primary nocturnal enuresis patients.

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The dopamine D4 receptor (DRD4) promoter (-616; rs747302) has been associated with primary nocturnal enuresis (PNE); however, its relationship with neuroimaging has not been investigated. Therefore, we assessed the effects of the DRD4 -616 C/G single nucleotide polymorphism on the gray matter volume

Risperidone-induced enuresis in two children with autistic disorder.

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BACKGROUND Risperidone appears to be effective in treating behavioral problems in children with autistic disorder. Although increased appetite, weight gain, and sedation are among the most common side effects, risperidone-induced enuresis is rarely reported. METHODS We will present two cases with

Iatrogenic nocturnal eneuresis – an overlooked side effect of anti histamines?

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Nocturnal enuresis is a common disorder in childhood, but its pathophysiological mechanisms have not been fully elucidated. Iatrogenic nocturnal enuresis has been described following treatment with several psychotropic medications. Herein, we describe a 6-year-old child who experienced nocturnal

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