28 epileptic children with induced secondary nocturnal enuresis in valproate monotherapy.

232 epileptic children without induced secondary nocturnal enuresis in valproate monotherapy.

Epilepsy

Nocturnal Enuresis

The patients' history, clinical, demographic, and laboratory data were acquired.
The following tests and imaging studies are routinely done for epilepsy patients receiving valproate treatment and developed nocturnal enuresis, blood urea nitrogen (BUN), serum creatinine (Cr), urinary pH (before and after valproate therapy beginning and at enuresis onset), serum levels and therapeutic doses of valproate.
Urinary tract ultrasonography (with full and void bladder).
CT brain and EEG.

Clinical, EEG and laboratory assessment at presentation

Valproate

Mansoura University Hospital

Sleep Architecture in Valproate-induced Nocturnal Enuresis in Primary School and Preschool Children.

PSG in Valproate-induced Nocturnal Enuresis in Children

Follow‐up at least monthly interval for 6 month for the children kept on valproate monotherapy. The incidence of nocturnal enuresis and its frequency were reported

The incidence of the side effects that happened in children during treatment by valproate.

nocturnal enuresis/seizures

Sleep Architecture in Valproate-induced Nocturnal Enuresis in Primary School and Preschool Children.

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