nocturnal enuresis/serotonin

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Rs 6313 polymorphism in 5-hydroxytryptamine receptor 2A gene association with polysymptomatic primary nocturnal enuresis.

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BACKGROUND Tricyclic antidepressants (TCA) were used to treat nocturnal enuresis (NE) for decades of years although their real mechanisms are unknown. Recently, some case studies demonstrated the efficacy of selective serotonin reuptake inhibitors (SSRI) in the treatment of NE. Both TCA and SSRI

Relationship between fluvoxamine and stress barometer for nocturnal enuresis.

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BACKGROUND It has been reported recently that fluvoxamine (a selective serotonin reuptake inhibitor) is effective and safe for children with monosymptomatic nocturnal enuresis (MNE). However, the exact mechanism by which fluvoxamine is beneficial in the treatment of MNE remains unknown. One

Reversible nocturnal enuresis in children receiving SSRI with or without risperidone: presentation of five cases.

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Selective serotonin re-uptake inhibitors are indicated in a group of psychiatric disor ders childhood. Data about their use in the treatment of enuresis also exist. Voiding disorders related to their use have been reported. We present five patients in whom bed-wetting was observed during a treatment

Side effects of clozapine and some other psychoactive drugs.

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The recognition, management, and if possible prevention, of major cardiovascular, central nervous system, haematological, and metabolic adverse effects, including diabetes mellitus and weight gain, of antipsychotics and some other drugs used to treat mental illness is a topic of much debate.

Antidepressant use and off-label prescribing in children and adolescents in Dutch general practice (2001-2005).

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OBJECTIVE To study the use of antidepressants in children and adolescents in Dutch general practice in 2001 and 2005 and to determine off-label prescribing. METHODS Data were obtained from the Netherlands Information Network of General Practice (LINH) that comprised 97 practices in 2001 and 73

Tolerability of amine uptake inhibitors in urologic diseases.

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Inhibitors of serotonin (5-HT) and/or noradrenaline (NA) reuptake have been developed for pharmacological treatment of major depressive disorder. Insights in the role of 5-HT and NA in the neurological control of the lower urinary tract have also led to their application in common urological

Antidepressant prescription by British child psychiatrists: practice and safety issues.

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OBJECTIVE To evaluate the pattern of prescribing antidepressant (AD) drugs by British child psychiatrists with particular emphasis on the impact of newer-type (heterocyclic and selective serotonin reuptake inhibitor) agents on this practice and to assess the safety of AD use for children in terms of

Tricyclic Antidepressant Toxicity

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Tricyclic antidepressants (TCAs) were introduced in the late 1950s for the treatment of depression. However, with the advent of selective serotonin reuptake inhibitors (SSRIs) and other new antidepressants, the use of TCAs has become limited, although it is still used to treat depression that has

Iatrogenic nocturnal eneuresis – an overlooked side effect of anti histamines?

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Nocturnal enuresis is a common disorder in childhood, but its pathophysiological mechanisms have not been fully elucidated. Iatrogenic nocturnal enuresis has been described following treatment with several psychotropic medications. Herein, we describe a 6-year-old child who experienced nocturnal

Decreased high affinity 3H-imipramine binding in platelets of enuretic children and adolescents.

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High affinity 3H-imipramine binding sites have been demonstrated in human brain and platelet membranes. It has been suggested that these binding sites selectively label serotonin transporter or uptake sites. Since imipramine has a beneficial effect in the treatment of nocturnal enuresis, the present

A drug utilisation study of antidepressants in children and adolescents using the General Practice Research Database.

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OBJECTIVE To characterise prescribing patterns of antidepressants (ATDs) to children and adolescents aged < or =18 years in the UK. METHODS Subjects issued at least one ATD prescription between 1 January 1992 and 31 December 2001 were identified from the UK General Practice Research Database.

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