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ornithine/neoplasms

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10 resultat

Methods of treating cancer with herbacetin

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BACKGROUND OF THE INVENTION Polyamines play important roles in normal and cancer cell growth. Elevated ornithine decarboxylase (ODC) activity is observed in neoplastic tissues suggesting that this enzyme is a target for cancer prevention or treatment. Difluoromethylomithine (DFMO), an approved FDA

Inhibition of ornithine aminotransferase for the treatment of proliferative disorders

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FIELD OF THE INVENTION The invention relates to inhibition of ornithine aminotransferase (OAT) for suppression of tumor cells proliferation. More particularly, the invention relates to methods of treatment of proliferative disorders by inhibition of OAT, and further provides the use of OAT

Inhibition of ornithine aminotransferase for the treatment of proliferative disorders

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FIELD OF THE INVENTION The invention relates to inhibition of ornithine aminotransferase (OAT) for suppression of tumor cells proliferation. More particularly, the invention relates to methods of treatment of proliferative disorders by inhibition of OAT, and further provides the use of OAT

Predictive markers for polyamine inhibitor cancer therapies

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BACKGROUND OF THE INVENTION I. Field of the Invention The present invention relates generally to the fields of cancer biology and medicine. More particularly, it concerns methods for the diagnosis, prevention, and treatment of carcinomas and risk factors thereof. II. Description of Related

Agglutination of lymphocytes for diagnosing malignant tumor

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The invention relates to a process for the specific agglutination of lymphocytes of sensitized the peripheric blood, which is an important method in diagnostics for the detection of diseases accompanied by a changed agglutinability of the lymphocytes. E. J. Field and E. A. Caspary observed a changed

Polyamine analogs that activate antizyme frameshifting

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CROSS-REFERENCE TO RELATED APPLICATIONS Not applicable STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not applicable REFERENCE TO A COMPACT DISK APPENDIX Not applicable TECHNICAL FIELD The present invention relates to novel polyamines, their synthesis and use in pharmacological,
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to the field of prophylaxis and treatment of hypotension. Most particularly, the present invention proposes methods for the control and inhibition of hypotension or systemic shock through the administration of

Methods for the treatment of malignant disease in patients using citrulline containing amino acid solutions

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BACKGROUND OF THE INVENTION Reference is made to Applicant's co-pending applications, Ser. No. 820,517, filed Jan. 17, 1986 and Ser. No. 002,890, filed Jan. 13, 1987. FIELD OF THE INVENTION The present invention relates to improved formulations and methods for the detection of malignant disease in a

Methods for the reduction of difluoromethylornithine associated toxicity

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BACKGROUND OF THE INVENTION The present application is a continuation-in-part of Ser. No. 820,517, filed Jan. 17, 1986. 1. FIELD OF THE INVENTION The present invention relates to improved formulations and methods for the detection of malignant disease in a patient. More particularly, the present

Methods and improved formulations for the determination and treatment of malignant disease in patients

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1. Field of the Invention The present invention relates to improved formulations and methods for the detection of malignant disease in a patient. More particularly, the present invention is directed to formulations which augment tumor related increases in a patient's polyamine level and which
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