Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
OBJECTIVE
A phase 1 study evaluated the QTc prolongation potential of siltuximab, a chimeric, anti-interleukin-6 mAb, in patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), or low-volume MM.
METHODS
Patients with baseline QTcF and QTcB ≤ 500
Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
BACKGROUND
The best treatment for polyneuropathy associated with IgM monoclonal gammopathy (MGUS) is unknown. Oral cyclophosphamide combined with prednisone showed limited efficacy in a previous open label pilot study. We therefore performed a double-blind, randomized, placebo-controlled study of
Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and anti-glomerular basement membrane (GBM) antibody disease are both rare autoimmune diseases. Monoclonal gammopathy of undetermined significance (MGUS) is one of the most common causes of plasma cell dyscrasias
Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
Dermato-neuro syndrome is a potentially fatal neurological complication of scleromyxedema consisting of fever, seizures, and coma. This is an overlooked scleromyxedema case of a 62-year-old female patient from 2-years ago. She was admitted to our ICU because of high fever, colloid speech, muscle
Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
OBJECTIVE
To report a case of primary hyperparathyroidism (PHPT) that presented with recurrent hypercalcemia due to multiple myeloma after successful parathyroidectomy.
METHODS
The initial manifestations, investigations, and postoperative follow-up of a case of hypercalcemia due to PHPT are
Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
Idiopathic systemic capillary leak syndrome (Clarkson's disease) is characterized by recurring attacks or increased capillary permeability, resulting in severe hypovolemic shock due to plasma extravasation from the intravascular compartment. Additional laboratory features include association with a
Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
A 47-year-old female patient presented nausea and vomiting for half a year and elevated serum creatinine for 3 days. Proximal renal tubular acidosis (RTA) complicated with anemiawas confirmed after admission. Secondary factors, such as autoimmune disease, drugs, poison, monoclonal gammopathy, were
Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
We report a colonic adenocarcinoma associated with diffuse submucosal deposition of a peculiar spheroid-type amyloid identified in the colon, terminal ileum, and appendix. A 65-year-old woman with past medical histories of hypertension, and chronic obstructive pulmonary disease, presented to the
Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
A 56-year-old black woman with diabetes mellitus was admitted for hypoglycemia and confusion. Her past medical history included breast cancer, for which she had undergone a left lumpectomy and then mastectomy for in-breast recurrence. Her oral intake had decreased during the past month because of
Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
A 34-year-old woman was admitted to our hospital in 1991, because of progressive headache, nausea and generalized edema. She was diagnosed as Crow-Fukase syndrome associated with plasma cell dyscrasia (IgA lambda type) in 1987, presenting with polyneuropathy, edema, and dermatologic changes. Those
Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
Renal disorders preceding multiple myeloma (MM) is a rare type of presentation for plasma cell dyscrasias. We report a case of 40-year-old female who first admitted to the hospital with symptoms and signs of weight loss, nausea and vomiting, and with findings of proteinuria renal dysfunction and
Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
Waldenström macroglobulinemia (WM) is a subset of lymphoplasmacytic lymphoma with bone marrow involvement, monotypic immunoglobulin (Ig) M and a light chain of neoplastic cells. A 68-year-old woman presented with fever, nausea, vomiting, and pancytopenia. Her serum albumin/globulin ratio was
Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
Amyloidosis is defined as the extracellular deposition of non-branching fibrils composed of a variety of serum-protein precursors. Secondary amyloidosis is associated with several chronic inflammatory conditions, such as rheumatologic or intestinal diseases, familial Mediterranean fever, or chronic
Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
Immunoglobulin D (IgD) monoclonal gammopathy is a rare subtype of multiple myeloma (MM) associated with a worse prognosis compared with other variants of MM. A 61-year-old man with no known past medical history presented with complaints of abdominal pain, nausea, and vomiting for three weeks.
Endast registrerade användare kan översätta artiklar
Logga in Bli medlem
Pauci-immune crescentic glomerulonephritis (PICGN) is most commonly associated with antineutrophil cytoplasmic antibodies (ANCA). We report a case of chronic, sclerosing ANCA-negative PICGN discovered when a patient presented with multiple myeloma. A 57-year-old woman presented with complaints of
Den mest kompletta databasen med medicinska örter som stöds av vetenskapen
Fungerar på 55 språk
Växtbaserade botemedel som stöds av vetenskap
Örter igenkänning av bild
Interaktiv GPS-karta - märka örter på plats (kommer snart)
Läs vetenskapliga publikationer relaterade till din sökning
Sök efter medicinska örter efter deras effekter
Organisera dina intressen och håll dig uppdaterad med nyheterna, kliniska prövningar och patent
Skriv ett symptom eller en sjukdom och läs om örter som kan hjälpa, skriv en ört och se sjukdomar och symtom den används mot. * All information baseras på publicerad vetenskaplig forskning