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pilocarpine/karies
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Pilocarpine alters caries development in partially-desalivated rats.
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This study examined the effect of pilocarpine on caries and saliva composition in rats with compromised salivary gland function. Eight litters of specific-pathogen-free female Sprague-Dawley rats were divided into five groups for surgery. Partial desalivation was performed in either of three ways:
Fluoride and pilocarpine reduce the risk of caries produced by chronic clomipramine treatment in rats.
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The effects of chronic clomipramine treatment on the incidence of caries in the rat and their prevention by fluoride and pilocarpine were investigated. One hundred and twenty male Wistar rats were divided into six groups, five experimental groups, one control group and treated with 50 mg/kg/day of
The effect of pilocarpine on dental caries in patients with primary Sjögren's syndrome: a database prospective cohort study.
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[The influence of atropine and pilocarpine on the development of experimental dental caries in rats].
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The effect of pilocarpine on dental caries in the rat.
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Reversal of fissure caries in the albino rat by stimulating salivary flow with pilocarpine.
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Infrared spectral characteristics of pilocarpine-stimulated saliva of normally caries-resistant animals compared with caries-resistant and -susceptible humans.
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The effect of pilocarpine in single or divided daily doses on the incidence of dental caries in the rat.
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[Effect of an organic inflammatory focus in the oral cavity on pilocarpine secretion of the paired salivary glands].
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Hyperglycemia and xerostomia are key determinants of tooth decay in type 1 diabetic mice.
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Insulin-dependent type 1 diabetes mellitus (DM) and oral diseases are closely interrelated. Poor metabolic control in diabetics is associated with a high risk of gingivitis, periodontitis and tooth loss. Salivary flow declines in diabetics and patients suffer from xerostomia. Reduced saliva
Sjögren's syndrome of the oral cavity. Review and update.
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Sjögren's syndrome is one of the most frequent autoimmune diseases. It is a chronic and systemic disorder predominantly found in women, and is characterized by the appearance of a lymphocytic inflammatory infiltrate, with dryness of the oral cavity and eyes, secondary to involvement of the salivary
The mechanism of histamine release induced by pilocarpine from different tissues: studies on rat peritoneal mast cells.
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Pilocarpine releases histamine from mast cells of cat submandibular gland and rat liver. In the salivary gland, histamine is released into the saliva and venous outflow. Atropine blocks the salivation, but not histamine release from the submandibular gland into the blood. Histamine release from the
Low-dose Pilocarpine Spray to Treat Xerostomia.
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Although pilocarpine hydrochloride tablets are currently indicated for the treatment of xerostomia, their adverse effects are frequently reported. The development of a new, low-dose pilocarpine solution for topical oral-cavity use is needed. This article discusses a few clinical trials to formulate
Transtympanic pilocarpine in tinnitus.
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In 48 patients who had neurosensory hypoacusia and whose main complaint was tinnitus, a 1% pilocarpine solution or a 2% carbachol Isopto solution was placed in the tympanic cavity by means of a No. 26 pencil-tipped lumbar puncture needle through the front quadrant of the eardrum. Patients were
Pilocarpine for Medication-induced Dry Mouth and Dry Eyes: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines
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Xerostomia is defined as dry mouth due to reduced salivary flow.1 As a result of this, patients may have decreased efficiency in chewing and swallowing and an increased risk of dental disease, such as dental caries (i.e., dental decay).1 Xerostomia may be caused by medications,
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