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Sida 1 från 26 resultat
KCNQ2 potassium channels
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FIELD OF THE INVENTION
The present invention concerns nucleic acids and proteins for potassium channels, as well as related vectors, host cells, processes for preparation, and methods of use. Included within the present invention are methods of screening for compounds that bind to and/or otherwise
Human kcnq5 potassium channel, methods and compositions thereof
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FIELD OF THE INVENTION
The present invention relates generally to the KCNQ family of potassium channels. More specifically, the present invention provides a new potassium channel polypeptide, KCNQ5, which was cloned and isolated from human tissue. Human KCNQ5 is found to be expressed primarily in
DNA encoding rodent KCNQ2 potassium channel
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FIELD OF THE INVENTION
The present invention concerns nucleic acids and proteins for potassium channels, as well as related vectors, host cells, processes for preparation, and methods of use. Included within the present invention are methods of screening for compounds that bind to and/or otherwise
KCNQ potassium channels and methods of modulating same
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FIELD OF THE INVENTION
The present invention concerns nucleic acids and proteins for potassium channels, as well as related vectors, host cells, processes for preparation, and methods of use. Included within the present invention are methods of screening for compounds that bind to and/or otherwise
KCNQ potassium channels and methods of modulating same
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FIELD OF THE INVENTION
The present invention concerns nucleic acids and proteins for potassium channels, as well as related vectors, host cells, processes for preparation, and methods of use. Included within the present invention are methods of screening for compounds that bind to and/or otherwise
Pharmaceutical combinations for the treatment of stroke and traumatic brain injury
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BACKGROUND OF THE INVENTION
This invention relates to methods of treating traumatic brain injury (TBI), ischemic stroke, or hypoxic brain injury, comprising administering to a patient in need of such treatment an NR2B subtype selective N-methyl-D-aspartate (NMDA) receptor antagonist in combination
Pharmaceutical combinations for the treatment of stroke and traumatic brain injury
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BACKGROUND OF THE INVENTION
This invention relates to methods of treating traumatic brain injury (TBI) or ischemic or hypoxic stroke, comprising administering to a patient in need of such treatment an NR2B subtype selective N-methyl-D-aspartate (NMDA) receptor antagonist in combination with one or
Bisarylamines as potassium channel openers
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FIELD OF THE INVENTION
This invention relates to the use of certain bisarylamines as potassium channel openers and to the treatment of diseases modulated by potassium channel opening. Additionally, this invention relates to novel compounds that are useful as potassium channel openers.
BACKGROUND OF
Heterocycles as potassium channel modulators
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BACKGROUND OF THE INVENTION
Ion channels are cellular proteins that regulate the flow of ions, including calcium, potassium, sodium and chloride, into and out of cells. These channels are present in all human cells and affect such processes as nerve transmission, muscle contraction and cellular
Heterocycles as potassium channel modulators
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BACKGROUND OF THE INVENTION
Ion channels are cellular proteins that regulate the flow of ions, including calcium, potassium, sodium and chloride, into and out of cells. These channels are present in all human cells and affect such processes as nerve transmission, muscle contraction and cellular
Heterocycles as potassium channel modulators
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BACKGROUND OF THE INVENTION
Ion channels are cellular proteins that regulate the flow of ions, including calcium, potassium, sodium and chloride, into and out of cells. These channels are present in all human cells and affect such processes as nerve transmission, muscle contraction and cellular
Fused ring heterocycles as potassium channel modulators
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FIELD OF THE INVENTION
This invention relates to the use of certain fused ring heterocycles as potassium channel modulators and to the treatment of diseases in which a potassium channel is implicated. Additionally, this invention relates to novel compounds that are useful as potassium channel
Fused ring heterocycles as potassium channel modulators
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FIELD OF THE INVENTION
This invention relates to the use of certain fused ring heterocycles as potassium channel modulators and to the treatment of diseases in which a potassium channel is implicated. Additionally, this invention relates to novel compounds that are useful as potassium channel
Fused ring heterocycles as potassium channel modulators
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FIELD OF THE INVENTION
This invention relates to the use of certain fused ring heterocycles as potassium channel modulators and to the treatment of diseases in which a potassium channel is implicated. Additionally, this invention relates to novel compounds that are useful as potassium channel
KCNQ potassium channel agonist, and preparation method therefor and use thereof
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FIELD
The present invention belongs to pharmaceutical field, and in particular, relates to a novel KCNQ potassium channel agonist, the preparation therefor and the use of the KCNQ potassium channel agonist or the pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising
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