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proteinuria/seizures

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Predictors of Incident Seizure in Systemic Lupus Erythematosus.

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OBJECTIVE The risk factors for incident seizures in systemic lupus erythematosus (SLE) were prospectively determined in a cohort study. METHODS A total of 2203 patients with SLE followed longitudinally in the Hopkins Lupus Cohort were analyzed. Demographic variables, clinical manifestations,

Convulsions in hypertensive, proteinuric primiparas more than 24 hours after delivery. Eclampsia or some other cause?

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A diagnosis of eclampsia has been considered inappropriate when the onset of a convulsion is greater than 24 hours after delivery. The observations presented here provide strong support for waiving the 24-hour rule, at least when convulsions from no other apparent cause and accompanied by

Presence of anti-La autoantibody is associated with a lower risk of nephritis and seizures in lupus patients.

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Previous reports suggest a protective role for anti-La autoantibody against the development of lupus nephritis. We studied the effect of anti-La on the prevalence of nephritis in a large cohort of lupus patients. In addition, we determined the association between anti-La and the presence of the

Proteinuria as a presenting sign of combined methylmalonic acidemia and homocysteinemia: case report

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Background: Disorders of the metabolism and absorption of vitamin B12 can lead to decrease in activity of methionine synthetase and methylmalonate coenzyme A mutase (MMUT), which results in increased levels of methylmalonic acid and
OBJECTIVE Eclampsia is a serious complication of pregnancy and remains a leading cause of maternal mortality worldwide. Magnesium sulfate is commonly used in the prophylaxis and treatment of eclampsia. However, uncertainty remain regarding its anticonvulsant mechanism(s) of action. This study

Severe tricuspid regurgitation and seizure on postpartum day 10: case report of late postpartum eclampsia.

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OBJECTIVE Late postpartum eclampsia is characterized by pre-eclampsia and tonic-clonic seizures presenting more than 48 hours postpartum. It is a rare, frightening and dangerous complication that requires rapid recognition and adequate treatment. METHODS We present a case of late postpartum

Water intoxication presenting as maternal and neonatal seizures: a case report.

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BACKGROUND We present an unusual case of fitting in the mother and newborn child, and the challenges faced in the management of their hyponatraemia due to water intoxication. METHODS A previously well 37-year-old, primigravid Caucasian woman presented with features mimicking eclampsia during labour.

Reversible posterior leukoencephalopathy syndrome in a patient of FSGS with heavy proteinuria.

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Reversible posterior leukoencephalopathy syndrome (RPLS) is a neurological syndrome characterized by headache, seizures, and visual loss, often associated with an abrupt increase in blood pressure. It was first described by Hinchey and colleagues in 1996 when they described a case series. RPLS has

A child with phenylketonuria and focal segmental glomerulosclerosis, the bright side of proteinuria.

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Phenylketonuria (PKU) is the most common inborn error of amino acid metabolism. Phenylalanine hydroxylase is the underlying deficient enzyme. If left untreated, growth failure, microcephaly, global developmental delay, seizures and severe intellectual impairment would characterize the clinical

Refractory generalized seizures as a possible side effect of bevacizumab in a colon cancer patient.

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Bevacizumab, which is a humanized monoclonal antibody against vascular endothelial growth factor, is used to treat metastatic cancers of the colon. Adverse effects common with bevacizumab treatment are hypertension, arterial-venous thrombosis, bleeding, gastrointestinal perforation, and proteinuria.
This report describes a 10-month-old infant who presented with generalised tonic clonic seizures following 2 days of vomiting, diarrhoea and a low-grade fever. The patient was moderately dehydrated and the blood investigations were remarkable for hyponatraemia (126 mEq/l), leukocytosis (19.4 ×
We investigated the effects of a cell-permeable superoxide dismutase mimetic, manganese(III) tetrakis(1-methyl-4-pyridyl)porphyrin (MnTMPyP) on blood-brain barrier (BBB) integrity following pentylenetetrazole (PTZ)-induced seizures in experimental preeclampsia symptoms induced by

Proteinuria in status epilepticus or eclampsia; a diagnostic dilemma.

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A 36-year-old primigravida with a history of temporal lobe epilepsy presented at 25 weeks of pregnancy with generalized tonic clonic seizures. The clinical picture was confused with eclampsia because of rising blood pressure and proteinuria. Clinical investigations, which included a lumbar puncture,

Lorlatinib induced proteinuria: A case report

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Introduction: Lorlatinib is an oral anaplastic lymphoma kinase (ALK) and C-ros oncogene (ROS1) tyrosine kinase inhibitor with excellent central nervous system (CNS) penetrability. It is currently approved for use as second line therapy

Acute kidney injury, seizures, and hypertonic hyponatremia secondary to mannitol intoxication in a dog.

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To describe a case of mannitol overdose associated with acute kidney injury (AKI), hypertonic hyponatremia, and neurologic abnormalities in a dog.A 10-year-old intact male Shiba Inu dog was referred to the emergency service of a veterinary teaching hospital
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