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Efficacy of Nifedipine Versus Hydralazine in Management of Severe Hypertension in Pregnancy

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Introduction Hypertension is the commonest medical complication of pregnancy. It is associated with high maternal and perinatal mortality, especially when severe. Hypertensive disorders of pregnancy constitute one of the five major causes of maternal morbidity and mortality in obstetric practice,

Keto-diet for Intubated Critical Care COVID-19

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Coronavirus disease (COVID-2019) is a devastating viral illness that originated in Wuhan China in late 2019. The number of confirmed cases worldwide has nearly reached 2 million and more than 125,000 people have died. Early studies from Wuhan reported a mortality rate of 2-3% with lower rates in

RescueTEE for In-hospital Cardiac Arrest (ReTEECA Trial)

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Rescue transesophageal echocardiography (RescueTEE) is an unplanned ultrasound examination performed on an urgent or emergent basis to diagnose causes of unexpected hemodynamic instability or cardiopulmonary arrest. The indication for RescueTEE is generally based on the individual patient's

Optimizing Gestational Weight Gain, Birth Weight and Other Perinatal Outcomes Among Pregnant Women at Risk of Hypertension in Pregnancy

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Background of the Project including Preliminary Observations Hypertensive disorders of pregnancy, including preeclampsia, complicate up to 10% of pregnancies worldwide, constituting one of the greatest causes of fetal growth restriction, preterm birth, low birth weight, perinatal mortality, and

Pre-eclampsia/Eclampsia in Italy Over the Years 2010-2016

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Poor placentation is considered a powerful predisposing factor for pre-eclampsia. Recently, it has been suggested that the occurrence of pre-eclampsia requires a combination of an excessive or atypical maternal immune response to the trophoblast and/or exaggerated endothelial activation as well as a

Temperature Control With an Esophageal Cooling Device in Post Cardiac Arrest Patients

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Temperature control in comatose survivors of cardiac arrest, is a critical aspect of these patients' care. In this context, mild temperature reduction for 24 hours post cardiac arrest has been shown to improve neurological outcomes. Hypothermia is commonly induced using a combination of internal and

Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation

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1.0 Background While atrial fibrillation (AF) is the most common sustained cardiac arrhythmia requiring therapy, it is also associated with increased risk of stroke, heart failure, myocardial infarction, dementia, and death. The number of Americans affected with AF is expected to surge to nearly 16

Chest Ultrasound of ER Patients With Cough or SOB

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Acute dyspnea (shortness of breath) is a common complaint for patients presenting to the Emergency Department (ED). The chest radiograph (CXR) has been the mainstay in evaluating patients with shortness of breath and often provides the timely diagnosis of pneumonia, pneumothorax, pulmonary edema,

The Effect of CRT on the Hypercapnic Ventilatory Response

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Sleep disordered Breathing is common in heart failure, affecting around half of patients. This may be Obstructive Sleep Apnoea due to loss of pharyngeal muscle tone (OSA, associated with obesity and snoring and predisposing to hypertension, heart attack and stroke) or Central Sleep Apnoea (CSA). CSA

Intermittent Hypoxia 2: Cardiovascular and Metabolism

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There are many physiological situations in which the organism is exposed to hypoxia, such as exercise and altitude. In addition some pathological situations also involve hypoxia, such as obesity, heart failure, respiratory failure and sleep apnea syndrome. Hypoxia associated with altitude is

Echocardiography Management for Patients Requiring Care for Non-Cardiac Surgery

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Step 1: Patient selection The first step in the EGHEM/EGAM process is appropriate patient selection. Patients who have any of the following cardiovascular risk factors and/or comorbidities and are scheduled for a non-cardiac surgery are candidates for EGHEM/EGAM: 1. Urology/gynecology/General

Combined High Frequency Oscillation and Tracheal Gas Insufflation for Severe Acute Respiratory Distress Syndrome

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OBJECTIVES AND UNDERLYING HYPOTHESIS High frequency oscillation (HFO) has beneficial physiological effects in acute respiratory distress syndrome (ARDS) [1-4]. A recent randomized controlled trial of HFO versus conventional mechanical ventilation (CMV) with traditional tidal volumes (10.1± 2.8

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