Pyrazole / inflammation

Regioselective synthesis of 1,5-diaryl pyrazole anti-inflammatory agents

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

BACKGROUND OF THE INVENTION The standard synthesis for pyrazoles involves the reaction of a .beta..epsilon..tau..alpha.-dicarbonyl compound with a hydrazine under mild conditions. See A. R. Katritzky in "The Principles of Heterocyclic Chemistry", Academic Press, New York (1968) at page 139. When the

1,3,5 trisubstituted pyrazole compounds for treatment of inflammation

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

FIELD OF THE INVENTION This invention is in the field of anti-inflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating inflammation and inflammation-associated disorders, such as arthritis. BACKGROUND OF THE INVENTION Prostaglandins play a major

1,3,5 trisubstituted pyrazole compounds for treatment of inflammation

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

FIELD OF THE INVENTION This invention is in the field of anti-inflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating inflammation and inflammation-associated disorders, such as arthritis. BACKGROUND OF THE INVENTION Prostaglandins play a major

Fused pyrazole derivatives, preparation method thereof, and use thereof in treatment of cancers, inflammation and immune diseases

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

TECHNICAL FIELD The present invention relates to novel fused pyrazole derivatives and their pharmaceutically acceptable salts thereof or pharmaceutical compositions comprising these compounds, and to methods of preparing these compounds. The present invention also relates to use of the fused

1,5-diphenyl pyrazole compounds for treatment of inflammation

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

FIELD OF THE INVENTION This invention is in the field of anti-inflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating inflammation and inflammation-associated disorders, such as arthritis. BACKGROUND OF THE INVENTION Prostaglandins play a major

Novel anti-inflammatory pyrazole derivatives and preparation thereof

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

BACKGROUND OF THE INVENTION This invention relates to novel anti-inflammatory pyrazole compounds. SUMMARY OF THE INVENTION In a compositional aspect, this invention relates to novel pyrazole compounds of Formula I ##STR2## wherein N IS 1, 2, 3, OR 4; R.sub.1, r.sub.2, r.sub.3, and R.sub.4 each are

Substituted pyrazoles for the treatment of inflammation

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

FIELD OF THE INVENTION This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating inflammation and inflammation-associated disorders, such as arthritis. BACKGROUND OF THE INVENTION Prostaglandins play a major

3,4-substituted pyrazoles for the treatment of inflammation

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

FIELD OF THE INVENTION This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating inflammation and inflammation-associated disorders, such as arthritis. BACKGROUND OF THE INVENTION Prostaglandins play a major

3,4-substituted pyrazoles for the treatment of inflammation

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

FIELD OF THE INVENTION This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating inflammation and inflammation-associated disorders, such as arthritis. BACKGROUND OF THE INVENTION Prostaglandins play a major

3,4-substituted pyrazoles for the treatment of inflammation

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

FIELD OF THE INVENTION This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating inflammation and inflammation-associated disorders, such as arthritis. BACKGROUND OF THE INVENTION Prostaglandins play a major

Pyrazole compounds as anti-inflammatory and analgesic agents

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

TECHNICAL FIELD This invention relates to pyrazole compounds, and their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of this invention have activity as prostaglandin E.sub.2 receptor antagonists, and these are useful in the

Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

BACKGROUND OF THE INVENTION It has been well established that T-cells play an important role in regulating immune response (F. Powrie and R. L. Coffman, Immunol. Today, 14, p. 270 (1993)). Indeed, activation of T-cells is often the initiating event in many inflammatory and autoimmune diseases. IL-2

Pyrazole derivatives as anti-inflammatory/analgesic agents

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

BACKGROUND OF THE INVENTION This invention relates to tricyclic pyrazole derivatives, methods of treatment and pharmaceutical compositions for the treatment of cyclooxygenase mediated diseases. The compounds of this invention inhibit the biosynthesis of prostaglandins by intervention of the action

Pyrazole-3-amines as anti-inflammatory agents

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

This invention relates to new heterocyclic compounds, processes for their preparation and compositions containing them. Chemical Abstracts, Vol 71, 1969, 22058Z describes several 3-aryl-5-methylpyrazol-3-amines but does not disclose any pharmaceutical uses of these compounds. The Indian Journal of

Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

BACKGROUND OF THE INVENTION This invention relates to heterocyclo-alkylsulfonyl pyrazoles, methods of treatment and pharmaceutical compositions for the treatment of cyclooxygenase mediated diseases, such as arthritis, neurodegeneration and colon cancer, in mammals, preferably humans, dogs, cats or

pyrazole/inflammation

Regioselective synthesis of 1,5-diaryl pyrazole anti-inflammatory agents

1,3,5 trisubstituted pyrazole compounds for treatment of inflammation

1,3,5 trisubstituted pyrazole compounds for treatment of inflammation

Fused pyrazole derivatives, preparation method thereof, and use thereof in treatment of cancers, inflammation and immune diseases

1,5-diphenyl pyrazole compounds for treatment of inflammation

Novel anti-inflammatory pyrazole derivatives and preparation thereof

Substituted pyrazoles for the treatment of inflammation

3,4-substituted pyrazoles for the treatment of inflammation

3,4-substituted pyrazoles for the treatment of inflammation

3,4-substituted pyrazoles for the treatment of inflammation

Pyrazole compounds as anti-inflammatory and analgesic agents

Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents

Pyrazole derivatives as anti-inflammatory/analgesic agents

Pyrazole-3-amines as anti-inflammatory agents

Heterocyclo-alkylsulfonyl pyrazoles as anti-inflammatory/analgesic agents

Den mest kompletta databasen med medicinska örter som stöds av vetenskapen