3 resultat
This invention pertains to a series of new derivatives of 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid, their synthesis, and the use of these compounds as platelet-activating factor antagonists, inhibitors of certain protein kinases, transcriptional inhibitors of COX-2 expression, and
BACKGROUND
Growth factors play an important role in angiogenesis, lymphangiogenesis, and vasculogenesis, and they regulate angiogenesis in a variety of processes. Undesirable or pathological angiogenesis is associated with diseases including diabetic retinopathy, psoriasis, cancer, rheumatoid
TECHNICAL FIELD
This invention relates to a pyridinecarboxamide derivative. More particularly, this invention relates to an N-(12-nitroxydodecyl)-6-piperazinylpyridine-3-carboxamide derivative, a process for the preparation thereof and a pharmaceutical preparation which comprises as an active