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FIELD OF INVENTION
The present invention is directed to compounds, their synthesis, and their use as antagonists, inverse agonists, modulators and or inhibitors of the Retinoic acid-related Orphan nuclear Receptor .gamma.t (ROR.gamma.t)/ROR.gamma.. In particular, the present invention is directed to
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FIELD OF INVENTION
The present invention is directed to compounds, their synthesis, and their use as antagonists, inverse agonists, modulators and or inhibitors of the Retinoic acid-related Orphan nuclear Receptor .gamma.t (ROR.gamma.t)/ROR.gamma.. In particular, the present invention is directed to
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FIELD OF INVENTION
The present invention is directed to compounds, their synthesis, and their use as antagonists, inverse agonists, modulators and or inhibitors of the Retinoic acid-related Orphan nuclear Receptor .gamma.t (ROR.gamma.t)/ROR.gamma.. In particular, the present invention is directed to
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FIELD OF THE INVENTION
The present invention relates to certain 3H-imidazo[4,5-b]pyridin-5-ol derivatives of Formula (Ia) and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the GPR81 receptor. Also provided by the present
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TECHNICAL FIELD
The present invention relates to a nitrogen-containing bicyclic compound or a pharmacologically acceptable salt thereof and a pharmaceutical composition comprising it as active ingredient.
More specifically, the present invention relates to (1) a compound of formula (I)
##STR00002##
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The present application is also related to U.S. patent application Ser. No. 12/761,312, filed on Apr. 15, 2010, now abandoned, which is incorporated by referent herein in its entirety.
FIELD
The present invention relates to differential air pressure devices. More particularly, the present invention
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein
R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl,
R.sub.b
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b
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BACKGROUND OF THE INVENTION
1. Field of Invention
The present invention generally relates to cycle exercisers and recumbent exercisers for physical therapy and/or general exercise as disclosed in U.S. Pat. No. 4,188,030, and more particularly, to the recumbent exercise machines described in U.S.
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FIELD
The invention relates to the treatment and prevention of various diseases or conditions caused by fat accumulation or vitamin deficiency.
BACKGROUND
After smoking, high fat diet is said to be the second most lethal habit, causing 300,000 deaths each year in the U.S. alone. High fat diet leads
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to the field of medical treatments for diseases and disorders. More specifically, the present invention relates to biologically active compounds that treat and prevent insulin resistance, impaired glucose tolerance,
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The present invention relates to a novel therapeutic use of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine or pharmacologically acceptable salts thereof for increasing the levels of IGF-1(insulin-like growth factor 1) for the therapeutic treatment or prophylaxis or cytological
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This is a 371 of PCT/IT97/00113 filed May 15, 1997.
The present invention relates to a novel therapeutic use of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine or pharmacologically acceptable salts thereof for increasing the levels of IGF-1 (insulin-like growth factor 1) for the
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TECHNICAL FIELD
The present invention relates to a new compound which is useful as a medicament or a cosmetic, to a process for producing the same and to a pharmaceutical composition comprising the same.
BACKGROUND ART
The melanocortin (MC) is a group of peptide hormones that are derived from
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