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Sida 1 från 45 resultat
Early Use of Long-acting Tacrolimus in Lung Transplant Recipients
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Lung transplantation is a life-saving therapy for patients with end-stage lung disease refractory to medical treatment, providing an improvement in both survival and quality of life.[1,2] Despite the benefits, patients are at risk for myriad side effects including infection, malignancy, neurologic
Symptomatic Trigeminal Neuralgia Attributed to Multiple Sclerosis - a Prospective Study in 60 Patients
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Background Among patients with TN, approximately 15% has secondary TN caused by another underlying condition such as multiple sclerosis or a tumor. Studies of classical TN patients have shown a strong association between a severe NVC of the trigeminal nerve and the painful side. This association has
Neurodegeneration Markers and Neurological Course in Severe Covid-19 Infection
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In animals, coronavirus infection is commonly associated with CNS involvement:
epilepsy and ataxia are observed during Feline Infectious Peritonitis (FIP) and virus is recovered in CSF, CNS is involved with strain-dependent severity in mice and rats infected by murine hepatitis virus, and murine
Gene Expression of Endocannabinoid System in Episodic and Chronic Migraine Patients
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Migraine is a neurovascular disease whose pathophysiology is far from being completely clarified. This is mainly due to the complex mechanisms that underlie migraine attack as well as its recurrence. The endocannabinoid system (ES) is a complex signalling system involved in different biological
Role of Simvastatin in Relapsing-Remitting Multiple Sclerosis
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Multiple sclerosis (MS), the most prevalent neurological disability, is an autoimmune-mediated disorder that affects the central nervous system (CNS) and often leads to severe physical or cognitive incapacitation as well as neurological problems in young adults . Multifocal zones of inflammation due
Cervical Spine Motion in the Elderly
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INTRODUCTION AND RATIONALE Physiological motion of the cervical spine is a subject of interest for medical specialists. Although the term 'physiological motion' is commonly used, a proper definition has been lacking for a long time. Segmental range of motion (sROM, e.g. the amount of sagittal
Detection of Pattern of Some Unusual Signs and Symptoms of Multiple Sclerosis
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Cerebral Blood Flow and tDCS
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Aim 1: To determine the effects of different stimulation intensities on relative cerebral blood flow (rCBF).
Currently, researchers use tDCS as an interventional modality to modulate the excitability of the brain, with measureable changes in both motor evoked potentials and physical performances.
DiagnosE Using the Central veIn SIgn
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The North American Imaging in MS Cooperative has reviewed the utility of the central vein sign (CVS) in the diagnosis of MS in 2015. They concluded that "To formally establish the clinical value of the CVS for the differential diagnosis at disease onset, a large, prospective, multicentre study
Potential Benefit for Non Invasive Vagus Nerve Stimulation Using GammaCore in the Treatment of Raynaud's Phenomena.
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Raynaud's phenomenon (RP) is a common vascular disorder that that affects approximately 10% of the general population. RP causes some areas of the body (i.e. fingers and toes) to feel cold and numb in response to cold exposure or emotional stress. Raynaud's phenomenon is characterized by reversible
Impact of Exercise on "Invisible" Symptoms and Quality of Life in Multiple Sclerosis Individuals
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This study will include individuals with multiple sclerosis including all MS types with EDSS from 0-8, who will be practicing at the Multiple Sclerosis Association in Rijeka for a period of 2 month, 2 times a week for 60 minutes per exercise (total 16h).
Participants will be randomly selected into 2
Efficacy of Botulinum Toxin A in Adult Subjects With Raynaud Phenomenon Secondary to Systemic Sclerosis
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In SSc, RP is present in 95% of the patients. Despite cold avoidance, RP attacks are severe, painful, affecting the quality of life, with frequent severe ischemic symptoms such as digital ulcers. Treating patients with RP secondary to SSc is extremely challenging. Oral calcium channel blockers, the
Safety and Tolerability of Perampanel in Amyotrophic Lateral Sclerosis Patients
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Management Of Acute Disseminating Encephalomyelitis
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Acute disseminated encephalomyelitis can occur at any age, but usually affects children and young adults. The mean age of clinical presentation in pediatric cohorts ranges from 5 to 8 years. The annual incidence of Acute disseminated encephalomyelitis is reported to be 0.4-0.8 per 100,000 and the
Noninvasive Brain Stimulation Training
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Introduction TMS is a non-invasive neuronal stimulation of surface areas of the brain that since its introduction in 1985 has been frequently used in neurology as a diagnostic and research tool. TMS uses magnetic fields to induce electrical currents that cross the nervous tissue depolarizing
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