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strychnine/blödning

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Fatal strychnine poisoning--a case report and review of the literature.

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A typical case of suicidal strychnine poisoning by a rodenticide is presented. The forceful muscular convulsions were accompanied by a clear sensorium. Pathological findings consisted of an early onset of postmortem rigidity and microscopic hemorrhages with minimal degenerative neuronal changes in

Pulmonary lesion induced by stress in magnesium-deficient rats. A light- and electron-microscopic study.

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A light- and electron-microscopic study was made of the lungs of magnesium (Mg)-sufficient and Mg-deficient pathogen-free weanling rats raised in a gnotobiotic environment. Mg-sufficient rats were studied unstressed, after mild auditory stress, or after strychnine seizures and showed essentially no
A light and electron microscopic study of Mg-deficient weanling rats showed structural changes of the lungs associated with the audiogenic seizure-shock episode, and with sudden, spontaneous death or spontaneous recovery after the shock episode. Pathogen-free weanling males were fed a Mg-deficient

Glycine reduces platelet aggregation.

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It has been demonstrated that a wide variety of white blood cells and macrophages (i.e. Kupffer cells, alveolar and peritoneal macrophages and neutrophils) contain glycine-gated chloride channels. Binding of glycine on the receptor stimulates Cl(-) influx causing membrane hyperpolarization that

Foodborne and Waterborne Disease in Canada - 1982 Annual Summary.

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Data on foodborne disease in Canada in 1982 are compared with those for 1981. A total of 988 incidents comprising 791 outbreaks and 197 single cases, caused illnesses in 7,384 persons in 1982. These figures are greater than for 1981, and, in fact, the numbers of incidents and cases are the highest

Pre- and postsynaptic inhibitory actions of methionine-enkephalin on identified bulbospinal neurons of the rat RVL.

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The effects of methionine-enkephalin (ME) on visualized bulbospinal neurons of the rostral ventrolateral medulla (RVL) were characterized in thin slices at 32 degrees C using the whole cell patch-clamp technique. Thirty-five percent of the recorded neurons were found to be tyrosine hydroxylase

Practical toxicologic diagnosis.

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Strychnine toxicosis is characterized by inducible tetanic seizures and metaldehyde poisoning by fine fasciculations progressing to generalized tremors and seizures. Intoxication with 1080 causes seizures, random running movements, vomiting, defecation, urination, acidosis and hyperglycemia.
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