Triterpenoid / inflammation

A-ring epoxidized triterpenoid-based anti-inflammation modulators and methods of use thereof

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BACKGROUND OF THE INVENTION I. Field of the Invention The present invention relates generally to the fields of biology and medicine. More particularly, it concerns compounds, compositions and methods for the treatment and prevention of diseases such as those associated with oxidative stress and

Derivatives of triterpenoid acids and uses thereof

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FIELD OF THE INVENTION This invention relates generally to the field of medicinal chemistry. More specifically, it relates to derivatives of triterpenoid acids, preferably derivatives of glycyrrhetinic acid, that have dual pharmacophoric properties, formulations containing such and their use to

Derivatives of triterpenoid acids and uses thereof.

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FIELD OF THE INVENTION This invention relates generally to the field of medicinal chemistry. More specifically, it relates to derivatives of triterpenoid acids, preferably derivatives of glycyrrhetinic acid, that have dual pharmacophoric properties, formulations containing such and their use to

Derivatives of triterpenoid acids and uses thereof

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FIELD OF THE INVENTION This invention relates generally to the field of medicinal chemistry. More specifically, it relates to derivatives of triterpenoid acids, preferably derivatives of glycyrrhetinic acid, that have dual pharmacophoric properties, formulations containing such and their use to

Methods of treating diseases using triterpenoid acid derivatives

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FIELD OF THE INVENTION This invention relates generally to the field of medicinal chemistry. More specifically, it relates to derivatives of triterpenoid acids, preferably derivatives of glycyrrhetinic acid, that have dual pharmacophoric properties, formulations containing such and their use to

C4 monomethyl triterpenoid derivatives and methods of use thereof

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BACKGROUND OF THE INVENTION I. Field of the Invention The present invention relates generally to the fields of biology and medicine. More particularly, it concerns compounds, compositions and methods for the treatment and prevention of diseases such as those associated with oxidative stress and

Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (E-selectin) and LECAM-1 (L-selectin)

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FIELD OF THE INVENTION This invention relates generally to the field of chemical compounds, and to methods of treatment and detection. More specifically, this invention relates to derivatives of triterpenoid acids, formulations containing such and their use in treating patients by binding to and/or

Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (e-selectin) and LECAM-1 (l-selectin)

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FIELD OF THE INVENTION This invention relates generally to the field of chemical compounds, and to methods of treatment and detection. More specifically, this invention relates to derivatives of triterpenoid acids, formulations containing such and their use in treating patients by binding to and/or

Triterpenoid compounds and methods of use thereof

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BACKGROUND OF THE INVENTION PGE2 belongs to the family of prostaglandins (PGs), which are a group of biologically active compounds found in virtually all tissues and organs. They are synthesized from the metabolism of a membrane lipid, arachidonic acid, by cyclooxygenases to the intermediate PGH2,

Certain chemical entities, compositions, and methods

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Provided are certain chemical entities, pharmaceutical compositions and methods for the treatment of inflammatory, neurodegenerative, neoplastic and autoimmune diseases. Numerous molecular and cellular events are associated with inflammatory disease processes. Such events may be defensive in the

Inhibitors and methods of use thereof

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BACKGROUND OF THE INVENTION I. Field of the Invention The present invention provides triterpenoid derivatives, as well as processes for the preparation of such derivatives. The invention also provides methods for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease,

Forms of CDDO methyl ester

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BACKGROUND OF THE INVENTION Triterpenoids are biosynthesized in plants by the cyclization of squalene. Although candidates for medicinal use, these naturally occurring molecules display relatively weak biological activity. Accordingly, chemists have sought to synthesize analogues of enhanced potency

Forms of CDDO methyl ester

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BACKGROUND OF THE INVENTION Triterpenoids are biosynthesized in plants by the cyclization of squalene. Although candidates for medicinal use, these naturally occurring molecules display relatively weak biological activity. Accordingly, chemists have sought to synthesize analogues of enhanced potency

Forms of CDDO methyl ester

Endast registrerade användare kan översätta artiklar

Logga in Bli medlem

BACKGROUND OF THE INVENTION Triterpenoids are biosynthesized in plants by the cyclization of squalene. Although candidates for medicinal use, these naturally occurring molecules display relatively weak biological activity. Accordingly, chemists have sought to synthesize analogues of enhanced potency

triterpenoid/inflammation

A-ring epoxidized triterpenoid-based anti-inflammation modulators and methods of use thereof

Derivatives of triterpenoid acids and uses thereof

Derivatives of triterpenoid acids and uses thereof.

Derivatives of triterpenoid acids and uses thereof

Methods of treating diseases using triterpenoid acid derivatives

C4 monomethyl triterpenoid derivatives and methods of use thereof

Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (E-selectin) and LECAM-1 (L-selectin)

Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (e-selectin) and LECAM-1 (l-selectin)

Triterpenoid compounds and methods of use thereof

Certain chemical entities, compositions, and methods

Inhibitors and methods of use thereof

Forms of CDDO methyl ester

Forms of CDDO methyl ester

Forms of CDDO methyl ester

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