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tuberculoma/seizures

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OBJECTIVE Simultaneous administration of phenytoin and isoniazid (INH) in tuberculous meningitis (TBM) or tuberculoma patients with seizures results in higher plasma phenytoin level and thus phenytoin intoxication. N-acetyltransferase 2 (NAT2) enzyme catalyses two acetylation reactions in INH
Treatment of tuberculous meningitis or tuberculoma has become complicated because of adverse drug interactions found amongst antitubercular and anticonvulsant drugs. The aim of the study is to evaluate the effect of simultaneously administered isoniazid (300 mg/day) and phenytoin (300 mg/day) on 60
A 35 year woman G2P0A1L0 at 16 weeks period of gestation, underwent termination of pregnancy for a fetus having a large lumbosacral meningomyelocele and Arnold chairi II malformation. She was a known treated case of tuberculoma of the brain who was not on any antiepileptics, and had been seizure

Intracerebral tuberculomas: A rare cause of seizure in an immunocompetent young male.

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Central nervous system (CNS) involvement occurs in about 1% of all tuberculosis (TB) cases, classically presenting as a meningitis. Intracerebral tuberculomas are a much rarer manifestation. We describe the case of a young black male who presented with new-onset seizure. Cerebral computerized

Tuberculoma-Induced Seizures.

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Seizures in human immunodeficiency virus (HIV) patients can be caused by a wide variety of opportunistic infections, and, especially in developing countries, tuberculosis (TB) should be high on the differential. In India, TB is the most common opportunistic infection in HIV and it can have several

Intracranial tuberculoma coexistent with uncinate seizures and violent behavior.

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New onset seizures and CNS tuberculoma.

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Tuberculoma presenting as occipital lobe seizures.

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Postpartum seizures due to tuberculoma in brain.

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Etiology and management of single small CT lesions in patients with seizures: understanding a controversy.

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Single, small (less than 1 cm) enhancing lesions are frequent findings on CT scans of Indian patients with seizures. These lesions have also been reported in patients from other parts of the world. They often resolve spontaneously and their etiology has been disputed for over a decade. Initially

Neurocysticercosis or tuberculoma - Which one has more epileptic potential?

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The duration of antiepileptic drug (AED) treatment in the management of seizures due to ring enhancing lesions (REL) remains a matter of debate. We undertook a prospective cohort study to look into the seizure patterns and incidence of recurrence in association with two of the most

Unusual cerebral tuberculoma.

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The unusual occurrence of a cerebral tuberculoma is herewith reported. The first manifestation of the tuberculous infection was an optic perineuritis. Treatment of the "papillitis" with steroids was followed by Jacksonian seizures--the signature of the tuberculoma. Surgical excision has produced a

Frontal lobe tuberculoma.

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Tuberculomas are usually infratentorial in children, and supratentorial lesions predominate in adults. We present a 4-year-old girl with multiple seizures, papilloedema and brisk reflexes. On investigation, she was found to have a large left parafalcine tuberculoma. She was treated with

Intracranial Tuberculoma in Native Races of Canada: With Special Reference to Symptomatic Epilepsy and Neurologic Features.

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In the period from 1947 to 1962, 49 cases of intracranial tuberculoma were observed and studied at the Charles Camsell Hospital, Edmonton, Alberta, among Canadian Indians and Eskimos. Thirty-six of these cases had no pre-existing clinical meningitis. Well-marked intracranial calcification was

Tuberculoma of the brain.

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Four patients with cerebral tuberculomas had presenting manifestations that included seizure disorder, exophthalmos, or extremity weakness. Although rare in this country, this diagnosis should not be overlooked in such patients, since combined surgical and medical therapy may be curative.
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