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tuberculosis/protease
Länken sparas på Urklipp
10 resultat
Prokaryotic proteasomal proteases of Mycobacterium tuberculosis (MTB) as targets for antibiotic therapy
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FIELD OF THE INVENTION
The present invention relates to methods of treating pathogenic infection in mammals.
BACKGROUND OF THE INVENTION
About two billion people are thought to be infected with the bacillus Mycobacterium tuberculosis ("Mtb"), the causative agent of tuberculosis ("TB"). The majority
Mycobacterium membrane protease as a target for inhibitors of intrabacterial pH homeostasis
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FIELD OF THE INVENTION
The present invention is directed to methods and compounds for inhibiting bacterial growth and treating a bacterial infection in a subject.
BACKGROUND OF THE INVENTION
When Metchnikoff discovered phagocytosis, he speculated that macrophages kill most ingested microbes by
Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections
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FIELD OF THE INVENTION
The present invention relates to compositions and methods for inhibition of bacterial infections comprising Gram negative, Gram positive, and acid fast bacilli in general and mycobacterium tuberculosis (TB), mycobacterium avium complex (MAC), and anthrax in particular, as well
Treatments for Mycobacterium tuberculosis
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FIELD OF INVENTION
The invention relates to methods of treating Mycobacterium tuberculosis infections.
SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy,
Multivalent vaccines comprising recombinant viral vectors
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TECHNICAL FIELD
The invention relates to the field of recombinant DNA and viral vector vaccines. Specifically, it relates to recombinant DNA and viral vectors harboring nucleic acids encoding multiple antigens and/or adjuvants.
BACKGROUND
Tuberculosis (TB) has been a major worldwide threat to human
Multivalent vaccines comprising recombinant viral vectors
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JOINT RESEARCH AGREEMENT
The claimed invention was made by or on behalf of the following parties to a joint research agreement: Crucell Holland B.V. and Aeras Global TB Vaccine Foundation. The agreement was in effect on or before the date the claimed invention was made, and the claimed invention was
Multivalent vaccines comprising recombinant viral vectors
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FIELD OF THE INVENTION
The invention relates to the field of recombinant DNA and viral vector vaccines. Specifically, it relates to recombinant DNA and viral vectors harboring nucleic acids encoding multiple antigens and/or adjuvants.
BACKGROUND OF THE INVENTION
Tuberculosis (TB) has been a major
Process for the enzymatic dispersal of Mycobacterium bovis - BCG
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BACKGROUND OF THE INVENTION
Vaccines containing various living avirulent cells of tubercle bacilli, in particular Bacillus Calmette-Guerin (BCG), an attenuated bovine tuberculosis organism (Mycobacterium bovis), have been used to induce immunity against acquired tuberculosis disease in man.
Compositions of, and methods for, alpha-1 antitrypsin Fc fusion molecules
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FIELD OF THE INVENTION
The present invention relates to compositions and methods for inhibition of bacterial infections comprising Gram negative, Gram positive, and acid fast bacilli in general and mycobacterium tuberculosis (TB), mycobacterium avium complex (MAC), and anthrax in particular, as well
Compositions of, and methods for, alpha-1 anti trypsin Fc fusion molecules
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FIELD OF THE INVENTION
The present invention relates to compositions and methods for inhibition of bacterial infections comprising Gram negative, Gram positive, and acid fast bacilli in general and mycobacterium tuberculosis (TB), mycobacterium avium complex (MAC), and anthrax in particular, as well
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