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Isolation and X-ray study of an anti-inflammatory active androstene steroid from Acacia nilotica.

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3beta-Acetoxy-17beta-hydroxy-androst-5-ene was isolated from aerial parts of Acacia nilotica (L.) Willd (Mimosaceae). The structure of this compound was established by spectral analysis and single crystal X-ray diffraction analysis. The steroid showed dose-dependent anti-inflammatory activity

Investigation of the anti-inflammatory activity of Acacia nilotica and Hibiscus sabdariffa.

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The aqueous extracts of Acacia nilotica and Hibiscus sabdariffa were tested for anti-inflammatory, analgesic and antipyretic activities in animal models. Acacia nilotica extract had an inhibitory effect on carrageenan induced paw edema and yeast-induced pyrexia in rats. It also produced a

Structure-activity relationship study of androstene steroids with respect to local anti-inflammatory activity.

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A sex hormone, 3beta-acetoxy-17beta-hydroxy-androst-5-ene (1) (CAS 1639-43-6), was isolated from aerial parts of Acacia nilotica. This compound is reported to have anti-inflammatory activity. In view of this, considering this molecule as a lead molecule different androstene compounds were

Optimized mixture of hops rho iso-alpha acids-rich extract and acacia proanthocyanidins-rich extract reduces insulin resistance in 3T3-L1 adipocytes and improves glucose and insulin control in db/db mice.

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Rho iso-alpha acids-rich extract (RIAA) from Humulus lupulus (hops) and proanthocyanidins-rich extracts (PAC) from Acacia nilotica exert anti-inflammatory and anti-diabetic activity in vitro and in vivo. We hypothesized that a combination of these two extracts would exert enhanced effects in vitro

In vitro biological activities of niloticane, a new bioactive cassane diterpene from the bark of Acacia nilotica subsp. kraussiana.

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BACKGROUND Acacia nilotica subsp. kraussiana was reported in African traditional medicine for the treatment of various ailments. Isolation of an active compound in this study from the bark extract may lead to the validation of its efficiency as a traditional crude drug. OBJECTIVE This study aimed to

γ-Sitosterol from Acacia nilotica L. induces G2/M cell cycle arrest and apoptosis through c-Myc suppression in MCF-7 and A549 cells.

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BACKGROUND Acacia nilotica is widely distributed in Asia. In India, it occupies an important place in the indigenous system of medicine against anti-inflammatory, antioxidant, cancers, and/or tumors. OBJECTIVE The purpose of this study is to investigate the inhibitory effect of Acacia nilotica

Gastroprotective effect of Acacia nilotica young seedless pod extract: role of polyphenolic constituents.

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OBJECTIVE To systematically evaluate antiulcer potential of Acacia nilotica in different ulcer models in rats. METHODS Different extracts [ethanolic, 50% hydroethanolic (50:50), 70% hydroethanolic (70:30) and aqueous] of young seedless pods were examined in pylorus ligation induced gastric ulcers in

In vitro evaluation of antioxidant and cytotoxic activities of lignin fractions extracted from Acacia nilotica.

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Lignin is one of the most important phytomacromolecule with diverse therapeutic properties such as anticancer, antimicrobial, anti-inflammatory and immune-stimulatory. The present study was carried out to evaluate the in vitro antioxidant, free radical scavenging and anti-proliferative/cytotoxic

Strong antioxidant phenolics from Acacia nilotica: profiling by ESI-MS and qualitative-quantitative determination by LC-ESI-MS.

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Acacia nilotica (L.) Del. syn is a species rich in polyphenolic constituents, in which catechins are hypothesized to possess antioxidant properties and to play a role in the anti-inflammatory activity of several plants. Due to the complexity of catechin derivatives, the investigation of this class

Tannins from Acacia mearnsii De Wild. Bark: Tannin Determination and Biological Activities.

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The bark of Acacia mearnsii De Wild. (black wattle) contains significant amounts of water-soluble components acalled "wattle tannin". Following the discovery of its strong antioxidant activity, a wattle tannin dietary supplement has been developed and as part of developing new dietary supplements, a

'Honey ointment': a natural remedy of skin wound infections.

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BACKGROUND Honey is a gift of nature, principally identified and valued to possess antimicrobial and anti-inflammatory activity and has been used as a natural remedy of wounds since ancient times. The objectives of this study were to evaluate the antimicrobial activity of honey against

Antidiabetic screening of commercial botanical products in 3T3-L1 adipocytes and db/db mice.

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Numerous botanicals are purported to improve glucose metabolism and diabetic risk factors with varying degrees of supportive evidence. We investigated 203 commercially available botanical products representing 90 unique botanical species for effects on lipogenic activity in differentiating 3T3-L1

Fruit pod extracts as a source of nutraceuticals and pharmaceuticals.

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Fruit pods contain various beneficial compounds that have biological activities and can be used as a source of pharmaceutical and nutraceutical products. Although pods or pericarps are usually discarded when consuming the edible parts of fruits, they contain some compounds that exhibit biological

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