wilms tumor/triglyceride

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Abdominal radiotherapy: a major determinant of metabolic syndrome in nephroblastoma and neuroblastoma survivors.

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BACKGROUND Reports on metabolic syndrome in nephroblastoma and neuroblastoma survivors are scarce. Aim was to evaluate the occurrence of and the contribution of treatment regimens to the metabolic syndrome. METHODS In this prospective study 164 subjects participated (67 adult long-term

[Late effect of treatment of nephroblastoma in patients treated in 1980-2001 in a single centre].

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BACKGROUND The aim of the study was to describe the late effects in a cohort of patients in long-term remission (> 5 years from end of treatment) diagnosed and treated for nephroblastoma at the single paediatric centre during 1980- 2001. METHODS 151 patients were examined for renal function, lipid

Adrenal function in adult long-term survivors of nephroblastoma and neuroblastoma.

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BACKGROUND Adrenal insufficiency, or relative insufficiency, might partly explain increased mortality rates in nephroblastoma and neuroblastoma survivors after unilateral adrenalectomy. OBJECTIVE To assess adrenal function and its metabolic effects in survivors after adrenalectomy. METHODS In this

Chylous ascites following surgical treatment for wilms tumor.

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OBJECTIVE Postoperative chylous ascites is a rare complication of retroperitoneal surgery that has considerable morbidity. We review the pathogenesis and management of chylous ascites following surgical treatment of Wilms tumor. METHODS We identified 9 children with chylous ascites after surgical

Metabolic syndrome detection with biomarkers in childhood cancer survivors

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Purpose: Augmented childhood nephroblastoma and neuroblastoma survival has increased long-term side effects as metabolic syndrome (MetS). Risk stratification is difficult after abdominal radiation because waist circumference

Phase I trial and pharmacokinetic study of all-trans-retinoic acid administered on an intermittent schedule in combination with interferon-alpha2a in pediatric patients with refractory cancer.

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OBJECTIVE To determine the maximum-tolerated dose (MTD) of all-trans-retinoic acid (ATRA) administered on an intermittent oral schedule with interferon-alpha2a (IFN-alpha2a) in children with refractory cancer, and whether the marked reduction in plasma ATRA concentrations observed with chronic daily

Salivary evaluation of pediatric patients with cancer, before and after antineoplasic treatment.

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OBJECTIVE This study evaluated the salivary biochemical and immunological status of children with cancer undergoing to antineoplasic treatment in an attempt to identify alternatives for a less invasive and less painful monitoring of these patients. METHODS Unstimulated whole saliva samples were

Overexpression of CCN3 inhibits inflammation and progression of atherosclerosis in apolipoprotein E-deficient mice.

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BACKGROUND Cysteine-rich 61/connective tissue growth factor/nephroblastoma overexpressed (CCN) 3 has been recently reported to play a role in regulating inflammation of vascular endothelial cells. However, the role of CCN3 in atherosclerosis, which is characterized by vascular inflammation, remains

Thiazolidinedione attenuate proteinuria and glomerulosclerosis in Adriamycin-induced nephropathy rats via slit diaphragm protection.

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OBJECTIVE The slit diaphragm (SD) of podocyte impairment contributes to massive proteinuria and progressive glomerulosclerosis in many human glomerular diseases. The aim of the study was to determine if thiazolidinedione (TZD) reduce proteinuria and glomerulosclerosis in focal segmental

Specificity of avian leukosis virus-induced hyperlipidemia.

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Rous-associated virus 7 (RAV-7) is a subgroup C avian leukosis virus which does not transform cells in vitro or carry an oncogene. When injected into 1-day-old hatched chicks, RAV-7 causes a low incidence of lymphoid leukosis after a latent period of several months. In contrast, infection of

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