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xanthine/inflammation
Länken sparas på Urklipp
Sida 1 från 28 resultat
Efficacy of Pentoxifylline as Add on Therapy in COVID19 Patients
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Study of Verinurad in Heart Failure With Preserved Ejection Fraction
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Evidence shows independent associations between hyperuricaemia and the risk of cardio-renal conditions, including heart failure (HF). Serum uric acid (sUA) is also a strong prognostic factor and correlates with other markers of poor prognosis in HF patients with preserved ejection fraction (HFpEF),
Pentoxifylline Augmentation in Schizophrenia
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there is some evidence for the role of phosphodiesterase (PDE) signaling system in pathophysiology of schizophrenia making this system a potential target for therapeutic agents. PDEs are a family of enzymes that hydrolyse cyclic nucleotides and thus play a key role in regulating intracellular levels
Effects of Allopurinol on Inflammation and Ultrasonographic Changes in People With Elevated Uric Acid But no Symptoms
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Gout is the most prevalent inflammatory rheumatological disease among young men, affecting about 4% of the general population. Caused by the deposit of monosodium urate (MSU) crystals which form because of high urate concentrations in serum. Currently, there is no universal definition for
A Study of Verinurad and Allopurinol in Patients With Chronic Kidney Disease and Hyperuricaemia
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Evidence shows independent associations between hyperuricaemia and the risk of hypertension, myocardial infarction, chronic kidney disease (CKD), type 2 diabetes, heart failure, and metabolic syndrome, including obesity Furthermore, gout, an inflammatory arthritis caused by deposition of monosodium
Uric Acid Metabolism, Endothelial Function and Oxidative Stress in Vegans and Omnivores.
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Non-meat eaters rise widely worldwide. This choice answers ideological, ecological or health concerns. Several vegetarian diets exist and the vegan diet is the most restricted one as it excludes all animal products, eggs and dairy.
Beside benefits on health and particularly on the cardiovascular
Allopurinol in Diabetes Mellitus and Multivessel Coronary Artery Disease
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This is a pilot study, PROBE design (prospective randomized open label blinded endpoints study), that will include 100 patients.
Patients will be recruited during their hospitalization in the cardiology department of Ichilov- Tel-Aviv Sourasky Medical Center.
It will include patients with known or
Uric Acid Effects on Endothelium and Oxydative Stress
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The goals of the research protocol are to clearly untie the respective roles of uric acid (UA) and xanthine oxidoreductase (XOR) pathways on endothelial function and oxidative stress in humans.
UA represents the end-product of purine metabolism due to the loss of uricase 15 million years ago in
Reactive Oxygen Species Following Aortic Valve Replacement
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Myocardial ischemia and reperfusion injury (MRI) related to cardio-pulmonary bypass has been linked to adverse clinical outcomes following cardiac surgery. Changes in ROS following SAVR have been well documented in the literature. Furthermore, pre-operative ROS markers such as malondialdehyde have
Endothelial Dysfunction and Oxidative Stress in Children With Sleep Disordered Breathing.
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Sleep disordered breathing (SDB) is a spectrum of diseases ranging from primary snoring to obstructive sleep apnoea (OSA). Recent studies suggested that the prevalence of SDB childhood was 7.4%. In patients with OSA, there are intermittent episodes of complete or partial obstruction leading to
Prednisone for Heart Failure Patients With Hyperuricemia
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Hyperuricemia in heart failure (HF) is linked to renal impairment, hemodynamic compromise, and inflammation. Hyperuricemic HF patients are characterized by worsening of renal function and fragile volume state, both of which restrict the use of non-steroidal anti-inflammatory drugs (NSAIDs) when
Effect of Allopurinol Administration on the Prevention of Muscle Mass Loss in Subject Immobilized.
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Impact of Fructose on Metabolism, Energy Homeostasis and MR Biomarkers in NAFLD
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Like obesity, NAFLD and NASH are closely linked to nutrition and the "Western diet" which is rich in saturated fats and refined sugars. Although fat consumption has remained relatively stable, the marked increase in dietary fructose consumption (more than doubling in the past 30 years alone)
Methylprednisolone N Acetylcysteine in Hepatic Resections
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Elective liver resection is performed mainly for benign and malignant liver tumors. The malignant tumors may arise primarily within the liver (hepatocellular carcinoma and cholangiocarcinoma) or represent metastases from malignancies of other organs. During hepatic resection, the risk of severe
A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Patients With Crohn's Disease
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Inflammatory Bowel Disease (IBD) in childhood are chronic relapsing and remitting inflammatory condition that have a significant impact on growth and development.
IBD involves a shift from a regulated intestinal immune response to one that is driven by unrestrained immune cell activation and
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