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Toward a new understanding of attention-deficit hyperactivity disorder pathophysiology: an important role for prefrontal cortex dysfunction.
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Recent advances in neurobiology have aided our understanding of attention-deficit hyperactivity disorder (ADHD). The higher-order association cortices in the temporal and parietal lobes and prefrontal cortex (PFC) interconnect to mediate aspects of attention. The parietal association cortices are
Oral trazodone is not effective therapy for erectile dysfunction: a double-blind, placebo controlled trial.
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OBJECTIVE
The unusual side effect of priapism associated with the antidepressant trazodone has led researchers to evaluate its use for the treatment of erectile dysfunction. Previous studies have shown nearly 70% efficacy in patients. Unfortunately, these studies have been anecdotal, retrospective
Postsynaptic alpha 2-adrenoceptors mediate melanosome aggregation in melanophores of the white-spotted rabbitfish (Siganus canaliculatus).
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The present investigation was undertaken to study the nature of neuro-melanophore junction in the white-spotted rabbit fish Siganus canaliculatus. In vitro experiments using split fin preparation indicated that melanophores of S. canaliculatus are highly responsive to potassium ions and adrenergic
Catecholamines contribute to exertional dyspnoea and to the ventilatory response to exercise in normal humans.
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BACKGROUND
Exogenous catecholamine administration in humans stimulates ventilation. The present study was designed to investigate whether increased endogenous catecholamine release influences objective measures of ventilation and subjective measures of breathlessness in normal
Role of alpha 1- and alpha 2-adrenergic receptors in the growth hormone and prolactin response to insulin-induced hypoglycemia in man.
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The effects of intravenous infusion of the nonselective alpha-adrenergic antagonist phentolamine or of the selective alpha 2-adrenergic antagonist yohimbine on growth hormone (GH), prolactin (PRL) and cortisol secretion during insulin-induced hypoglycemia were studied in 11 healthy young men. The GH
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