International Journal of Pharmaceutics 2004-Jun

Cathepsin K inhibitor-polymer conjugates: potential drugs for the treatment of osteoporosis and rheumatoid arthritis.

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Ingia / Ingia

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D Wang

W Li

M Pechar

P Kopecková

D Brömme

J Kopecek

KIFUNGU: 15158970

DOI: 10.1016/j.ijpharm.2003.03.003

BioSeek: 15158970

Maneno muhimu

Kikemikali

The role of the newly discovered cysteine protease, cathepsin K, in osteoporosis and rheumatoid arthritis is reviewed. The current development of cathepsin K inhibitors and their targeted delivery using synthetic polymer carriers are discussed. Future challenges and possible strategies to improve these delivery systems are addressed.

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Herbal & Natural Medicine

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