British Journal of Pharmacology 1973-Oct

The inhibition of histamine uptake and metabolism by burimamide in the guinea-pig atrium and in mouse neoplastic mast cells, in vitro.

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Ingia / Ingia

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R Fantozzi

P F Mannaioni

F Moroni

KIFUNGU: 4152220

PMC: PMC1776390

BioSeek: 4152220

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Kikemikali

Burimamide, an H(2)-receptor blocking agent, has been shown capable of blocking the uptake and metabolism of [(14)C]-histamine, both in the guinea-pig isolated atrium and in murine neoplastic mast cells. This occurs even at concentrations far below the dose range capable of blocking the positive chronotropic effect of histamine in the isolated atrium. In the atrium, very low concentrations of burimamide were found capable of blocking histamine metabolism.

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Herbal & Natural Medicine

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The inhibition of histamine uptake and metabolism by burimamide in the guinea-pig atrium and in mouse neoplastic mast cells, in vitro.

Maneno muhimu

saratani

histamine

Kikemikali

Hifadhidata kamili ya mimea ya dawa inayoungwa mkono na sayansi