caffeine/atrophy

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Testicular atrophy and impaired spermatogenesis in rats fed high levels of the methylxanthines caffeine, theobromine, or theophylline.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

Experiments were designed to determine the effects of feeding the methylxanthines caffeine, theobromine, or theophylline to 4- to 6-week-old male rats at a dietary level of 0.5 percent for periods ranging from 14 to 75 weeks. In the first two experiments, Osborne-Mendel rats were fed the test

Testicular atrophy and impaired spermatogenesis in rats fed high levels of the methylxanthines caffeine, theobromine, or theophylline.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

Experiments were designed to determine the effects of feeding the methylxanthines caffeine, theobromine, or theophylline to 4- to 6-week-old males rats at a dietary level of 0.5 percent for periods ranging from 14 to 75 weeks. In the first two experiments, Osborne-Mendel rats were fed the test

Influence of caffeine on 3,4-methylenedioxymethamphetamine-induced dopaminergic neuron degeneration and neuroinflammation is age-dependent.

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Ingia / Ingia

Previous studies have demonstrated that caffeine administration to adult mice potentiates glial activation induced by 3,4-methylenedioxymethamphetamine (MDMA). As neuroinflammatory response seems to correlate with neurodegeneration, and the young brain is particularly vulnerable to neurotoxicity, we

Caffeine alleviates the deterioration of Ca(2+) release mechanisms and fragmentation of in vitro-aged mouse eggs.

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Ingia / Ingia

The developmental competence of mammalian eggs is compromised by postovulatory aging. We and others have found that in these eggs, the intracellular calcium ([Ca(2+)](i)) responses required for egg activation and initiation of development are altered. Nevertheless, the mechanism(s) underlying this

Caffeine treatment aggravates secondary degeneration after spinal cord injury.

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Ingia / Ingia

Spinal cord injury (SCI) often results in some form of paralysis. Recently, SCI therapy has been focused on preventing secondary injury to reduce both neuroinflammation and lesion size so that functional outcome after an SCI may be improved. Previous studies have shown that adenosine receptors (AR)

Caffeine protects against combined paraquat and maneb-induced dopaminergic neuron degeneration.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

Environmental exposures suspected of contributing to the pathophysiology of Parkinson's disease (PD) include potentially neurotoxic pesticides, which have been linked to an increased risk of PD. Conversely, possible protective factors such as the adenosine antagonist caffeine have been linked to a

Alteration in the progression of dopamine neuron degeneration: may caffeine offer new perspective?

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Ingia / Ingia

Neuroprotection by caffeine and more specific A2A receptor antagonists in animal models of Parkinson's disease.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

A remarkable convergence of epidemiologic and laboratory data has raised the possibility that caffeine reduces the risk of developing Parkinson's disease (PD) by preventing the degeneration of nigrostriatal dopaminergic neurons. The authors review the evidence that caffeine and more specific

Delayed caffeine treatment prevents nigral dopamine neuron loss in a progressive rat model of Parkinson's disease.

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Ingia / Ingia

Parkinson's disease (PD) is characterized by a prominent degeneration of nigrostriatal dopamine (DA) neurons with an accompanying neuroinflammation. Despite clinical and preclinical studies of neuroprotective strategies for PD, there is no effective treatment for preventing or slowing the

The effects of caffeine on marksmanship accuracy and reaction time: a systematic review.

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Ingia / Ingia

Military and law enforcement personnel are required to maintain optimal marksman accuracy and reaction time during extended duty hours amidst environmental stressors. Although caffeine is commonly used to mitigate the consequences of fatigue, the effects of caffeine on marksmanship accuracy are

Caffeine for the prevention of injuries and errors in shift workers.

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Ingia / Ingia

BACKGROUND Sleepiness leads to a deterioration in performance and attention, and is associated with an increased risk of injury. Jet lag and shift work disorder are circadian rhythm sleep disorders which result in sleepiness and can elevate injury risk. They create a need for individuals to operate

Caffeine induces cardiac and other malformations in the rat.

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Ingia / Ingia

At various gestational periods, caffeine was injected intra-arterially or intraperitoneally into pregnant rats. The teratogenic effects of caffeine on the fetal heart were dose dependent and detectable at relatively low concentrations. The most susceptible stage was during septation of the heart.

Increased detection and yield of adenovirus in caffeine-stabilised KB cell monolayers.

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Ingia / Ingia

Viable monolayers of KB cells were maintained without passage for up to one year by adding 2 X 10(-3) M caffeine to the medium, while untreated monolayers degenerated after 2 weeks. When adenoviruses type 2 and 17 were titrated on caffeine-stabilised KB cells, the late breakthrough of cytopathic

[Caffeine and smoking-induced changes in the behavior of car drivers].

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Ingia / Ingia

The authors examined changes in the behaviour of car drivers under the effect of coffeini matrii benzoici in doses of 250 mg (125 mg pure caffeine) and 500 mg (250 mg pure caffeine) in a single experimental group who had been exposed, prior to that, to a zero control experiment. The behaviour

Caffeine withdrawal in normal school-age children.

Watumiaji waliosajiliwa tu ndio wanaweza kutafsiri nakala

Ingia / Ingia

OBJECTIVE Caffeine is widely consumed by children around the world. The purpose of this study was to determine whether children manifest withdrawal effects after cessation of caffeine intake. METHODS Thirty normal children completed the single-blind, within-subjects, repeated-measures study with

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