Ukurasa 1 kutoka 590 matokeo
OBJECTIVE
Many that survive an aneurysmal subarachnoid hemorrhage experience lasting physical disability, which might be improved by medications with effects on the dopaminergic, serotonergic, and brain-derived neurotrophic factor neurotransmitter systems. But it is not clear which patients are most
Serum dopamine beta-hydroxylase activity was followed in seven patients who had experienced primary subarachnoid hemorrhage resulting from a ruptured intracranial aneurysm. This preliminary study suggested that dopamine beta-hydroxylase levels were initially elevated following subarachnoid
Plasma catecholamines, cyclic AMP and metabolic substrates in hemorrhagic shock of rats was studied in 4 groups of animals: 1) Control rats, 2) rats with adrenal demedullation, 3) rats with 6-OH-dopamine induced chemical sympathectomy, and 4) rats with combined demedullation and sympathectomy. The
Dopamine has been reported to increase renal blood flow during hemorrhagic shock. Since this effect would be of considerable benefit in shock, the effect of dopamine on hemorrhagic hypotension to 70 mm Hg for five hours was studied. Plasma renin activity and outer cortical blood flow were
The present study was conducted to determine if selective prejunctional dopamine receptor agonists will be useful in improving renal hemodynamics in acute hemorrhagic shock in anesthetized mongrel dogs. Both bromocriptine and N-n-propyl-N-n-butyl dopamine (PBDA) effectively increased renal blood
Hemorrhagic pancreatitis was induced in cats by perfusing pancreatic enzymes through a pancreatic duct after the administration of intragastric ethanol. Dimethyl prostaglandin E2 was administered concurrently. In the first study, dopamine's antiinflammatory effect on the pancreas was determined in
Hemorrhage after traumatic brain injury (TBI) in cats produces significant decreases in cerebral oxygen delivery (DcereO2) and electroencephalographic (EEG) activity. To determine whether effective treatments for the separate insults of TBI and hemorrhagic shock would also prove effective after the
Effects of dopamine and dobutamine in a dose of 5, 10 or 20 micrograms.kg-1.min-1 on hepatic blood flow and hepatic metabolism were studied in normotensive and hemorrhagic hypotensive (MAP 50mmHg) pigs during 1 MAC enflurane anesthesia. PaCO2 was maintained within a physiological range (30-35mmHg)
Gut metabolism may become anaerobic before the whole body during progressive phlebotomy in dogs. Because dopamine has selective mesenteric vasodilator effects, we asked whether dopamine could delay onset of bowel ischemia during hemorrhagic shock. We studied whole body and gut O2 consumption (VO2)
BACKGROUND
Inflammasomes are involved in diverse inflammatory diseases. Previous study reported that the neurotransmitter dopamine inhibited NLRP3 inflammasome activation via dopamine D1 receptor (DRD1). The present study aims to investigate the role of DRD1 on neuroinflammation in intracerebral
Controlled hemorrhagic hypotension in anesthetized dogs causes progressive increases in dopamine beta-hydroxylase (DBH) and catecholamine (CA) plasma levels and in heart rate. The concentration (units per milliliter) and the calculated total plasma content of DBH activity [(units circulating +
In 24 patients with subarachnoid hemorrhage (SAH) who were admitted within 48 hours after the onset, the activity of dopamine-beta-hydroxylase (DBH) in peripheral venous plasma was analyzed applying the method described by Nagatsu and Udenfriend (Clin. Chem., 18: 980-983, 1972) with a minor
The objective of this study was to determine the effectiveness of lactated Ringer's (LR) solution, sodium hydroxyethyl starch (hetastarch), and dopamine (DA) on diaphragm shortening (DS), diaphragm blood flow (DBF), diaphragm hydrogen peroxide (H2O2), and diaphragm apoptosis following hemorrhagic
The effects of intravenous nitroglycerin (NTG) combined with dopamine on intracranial pressure (ICP) and cerebral arteriovenous oxygen difference (AVDO2) were studied in 11 patients with acute subarachnoid haemorrhage (SAH). The study was performed on Days 1 to 3 of SAH after aneurysmal clipping.
Acute hemorrhagic pancreatitis (HP) is probably associated with decreased blood flow in its early phases, as well as with an increase in microvascular permeability. Dopamine (DOP; 5 micrograms/kg-min) is a splanchnic vasodilator, and also has beta-adrenergic effects that can prevent increases in