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epilepsy/mhindi

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Ultrasound-induced epileptiform activity in rats treated with hexachlorobenzene.

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Ingia / Ingia
Hexachlorobenzene (HCB), an environmental contaminant, has caused spontaneous convulsions in infants and neonate rats born and breast-fed from exposed mothers as well as in weanling rats exposed for many weeks. This study aimed to determine if HCB causes epileptiform convulsions in adult rats. For

Fish oil (n-3 fatty acids) in drug resistant epilepsy: a randomised placebo-controlled crossover study.

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Ingia / Ingia
BACKGROUND n-3 fatty acids inhibit neuronal excitability and reduce seizures in animal models. High-dose fish oil has been explored in two randomised trials in drug resistant epilepsy with negative results. We performed a phase II randomised controlled crossover trial of low-dose and high-dose fish
Nuclear factor erythroid-2 related factor 2 (Nrf2) is a transcription factor, which activates the anti-oxidative stress response pathway. In epilepsy, oxidative stress is one of the key factors in the progression of the disease. So, the neuroprotective role of dimethyl fumarate (DMF), a Nrf2 pathway

Effects of hexachlorocyclohexane isomers on the acquisition of kindled seizures.

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Ingia / Ingia
The effects of three isomers (alpha, beta, gamma) of hexachlorocyclohexane on the acquisition and expression of kindled amygdaloid seizures were compared. Treatment with corn oil (vehicle) was compared with daily 5 mg/kg doses of the isomers for 15 days during kindling procedures. The results

Effects of two isomers of hexachlorocyclohexane (HCH) on cortical beta-adrenoceptors in rat brain.

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Ingia / Ingia
Two isomers of hexachlorocyclohexane (HCH) have profound effects on the acquisition of kindled seizures. The gamma-isomer (lindane, gamma-HCH) increases the rate of acquisition in a dose-related manner whereas the beta-isomer (beta-HCH) has the opposite effect, retarding the rate in a dose-related
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