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Stress Ulcer Prophylaxis Versus Placebo in Critically Ill Infants With Congenital Heart Disease

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Ingia / Ingia

Background & Significance. Approximately 36,000 infants are born with congenital heart disease (CHD) in the United States each year, often requiring surgical intervention in the first year of life. They are vulnerable to postoperative morbidities including infection, growth failure and

Re-EValuating the Inhibition of Stress Erosions (REVISE) Trial

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Ingia / Ingia

Background: For 40 years, pharmacologic prevention of stress ulcer-related gastrointestinal (GI) bleeding with acid suppression has been the standard of care for mechanically ventilated critically ill patients. Worldwide, proton pump inhibitors (PPIs) are more commonly used than histamine-2-receptor

Gastrointestinal Complications in Association With Oropharyngeal and Respiratory Infections in Mechanical Ventilation

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Ingia / Ingia

Hospital acquired or nosocomial infections continue to be an important cause of morbidity and mortality. The critically ill patient is at particular risk of developing intensive care unit acquired infection, with the lungs being especially vulnerable. Nosocomial bacterial pneumonia occurring after

Effects of Enteral Nutrition on Stress Ulcer Hemorrage. Multicenter Randomized Controlled Trial

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Ingia / Ingia

Mucosal erosions can occur on luminal surface of stomach in approximately 75-100% patients during the first 24 hours of intensive care unit admission. These erosions often cause bleeding with penetrating superficial capillaries. Clinically significant bleeding (Significant decrease in blood pressure

MR Imaging- Guided High Intensity Focused Ultrasound (HIFU) Therapy of Bone Metastases

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Ingia / Ingia

Clinical Background Bone metastasis give rise to major complications that lead to significant morbidity and impairment of life quality. The most common primary for bone metastasis is prostate, lung and breast carcinoma. These three have the highest cancer incidence in the USA with up to 85%

Tryptase Level as a Marker of Complications in Transcatheter Aortic Valve Replacement

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Ingia / Ingia

Inflammation is known to have a detrimental effect on outcome of patients with myocardial infarction (MI) [1, 2] as well as reperfusion injury (RI) [3]. Previous trials have shown correlation between the extent of an inflammatory response and postoperative complications and worse outcomes in

Ibuprofen vs Acetaminophen for AMS Prevention

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Ingia / Ingia

Acute mountain sickness (AMS) is a well-known disorder in sojourners to high altitude (>2000m) characterized by headache, nausea and tiredness, akin to hangover-like symptoms. The Lake Louise criteria for AMS was primarily developed to allow uniformity in comparing the prevalence of AMS in different

Histamine Glutamate Antagonism in Stroke

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Ingia / Ingia

If the subject decides to take part in this study, the subject will be placed randomly in the treatment group or the standard of care group. This means: The subject will be given either the treatment drugs with standard of care for stroke or only standard of care. If the subject is placed in the

Mechanisms of N-acetylcysteine Mediated Vascular Adverse Effects

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Ingia / Ingia

In this study the investigators test the following hypotheses: 1. NAC causes dose-dependent vasodilatation associated with histamine release in vivo. 2. Release of other mediators, known to be associated with anaphylaxis, does not occur during anaphylactoid reactions to NAC. 3. Paracetamol has a

Repeated Nasal Challenge in Skin Prick-puncture Negative and Intradermal Positive Dust Mite Allergic Rhinitis Patients

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Ingia / Ingia

All patients will be seen in the outpatient setting. After skin testing, subjects meeting established criteria will be placed in the study. Subjects will use dust mite Dermatophagoides pteronyssinus extract or placebo nasal spray at home for 2 weeks, with a 1 month washout period followed by 2 weeks

PPI vs H2RA in Patients With Helicobacter Pylori-Negative Idiopathic Bleeding Ulcers

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Ingia / Ingia

Peptic ulcer disease used to be caused by a bacterial infection (Helicobacter pylori) in the stomach or the use of certain painkillers (nonsteroidal anti-inflammatory drugs or NSAIDs). However, there has been an increasing trend of peptic ulcer disease with unknown cause (idiopathic ulcer) worldwide

Economic Outcomes of Enteral and Parenteral Proton Pump Inhibitor (PPI) Use in the Intensive Care Unit (ICU)

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Ingia / Ingia

BACKGROUND AND SIGNIFICANCE: Detail: Proton pump inhibitors (PPIs) are commonly used in intensive care unit (ICU) patients for various clinical conditions, including acute stress related gastrointestinal bleeding (ASRGIB) and clinically significant upper gastrointestinal bleeding (UGIB). Although

Peptic Ulcer Disease in Ischemic Heart Patients Taking Aspirin and Clopidogrel With or Without Proton Pump Inhibitor

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Ingia / Ingia

Patients are eligible if they have received PCI for their stenotic coronary arteries. Patients who had a past history of PUD without complication, who have taken aspirin or clopidogrel before enrolling for their CV disease will be allowed to enroll. Patients are excluded if they have New York Heart

Effects of Oral Rabeprazole on the Prevention of Ulcer Bleeding Following Endoscopic Mucosal Resection

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Ingia / Ingia

- Endoscopic mucosal resection (EMR) is less invasive than surgery and is known to be general treatment for early gastric cancer or gastric adenoma when patients' quality of life is taken into consideration. However, major complications such as bleeding and perforation remain to be problematic.1-5

Hypnotherapy for Prevention of Relapse in Ulcerative Colitis: a Randomised, Single-blind, Controlled Clinical Trial

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Ingia / Ingia

SCIENTIFIC ABSTRACT There is increasing evidence that relapse of ulcerative colitis (UC) can be provoked by psychological stress. When this study was planned, there were no proper scientific studies to find out whether stress reduction can improve the course of UC. Hypnotherapy is a technique by

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