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Can Levothyroxine Treatment Reduce the Development of Cardio-metabolic Disorder in Subclinical Hypothyroidism?

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Ingia / Ingia

Sub-clinical hypothyroidism (SCH) is a form of thyroid dysfunction in which the thyroid-stimulating hormone (TSH) level is high, while serum total/free thyroxine (T4/fT4) is within the normal reference range . SCH is mostly detected accidentally as most of the patients manifest few or no signs of

The Impact of Subclinical Hypothyroidism on Cardiovascular System

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Ingia / Ingia

Subclinical hypothyroidism (SCH) is defined as a condition that characterized by elevated serum thyroid-stimulating hormone (TSH) concentrations (TSH: >4.5 mu/l), while circulating thyroxine (T4) and tri- iodothyronine (T3) levels remain within the normal range. Depending on the extent of serum TSH

Correlations Between Oxidative Stress Biomarkers, h-FABP and Left Ventricular Dysfunction in Patients With Acute Myocardial Infarction Undergoing Primary PCI

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Ingia / Ingia

Gathered data: - Descriptive general demographic data; - Previous pathologies (ischemic heart disease, peripheral arterial disease, stroke, heart failure, previous percutaneous coronary interventions, coronary artery bypass grafting - CABG, known renal disease); - Cardiovascular risk factors (age,

Metabolic and Physiological Changes During Minor Orthopaedic Surgery in Otherwise Healthy Patients

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Ingia / Ingia

Oxygen supplement during general anaesthesia During general anaesthesia the use of supplemental oxygen to avoid life-threatening hypoxaemia has been common practice for many years. This lead to supranormal levels of oxygen in the lungs (hyperoxia) and most patients also have supranormal levels of

Prevalence of Thyroid Function Abnormalities in HIV-infected Patients

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Ingia / Ingia

Since the appearance of high-efficiency anti-retrovirals (HAARTs) in the treatment of Human Immunodeficiency Virus (HIV), several studies have shown an increase in the prevalence of hypothyroidism (frank, rough or low hypothyroidism T4) in cohorts of HIV-infected adults and children. More

Correlation of Uterine and Umbilical Arteries Doppler With Placental Pathology in IUGR

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Ingia / Ingia

When indicated, a conservative management plan of IUGR was undertaken according to a defined protocol including antenatal visits, ultrasound surveillance. The frequency of fetal surveillance was assessed at each visit according to the maternal and fetal conditions. Doppler studies were performed

Aspirin and Renal Disease Progression in Patients With Type 2 Diabetes

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Ingia / Ingia

Epidemiological data show that type 2 diabetes has an epidemic trend worldwide. The increase in food intake, the greater availability of refined grains and the reduction of physical activity had, in fact, negative effects in most areas. It is expected that the number of people suffering from

SNPs in the DNase 1 Gene Impair Its Activity and Are Increased in a STE-ACS Patient Cohort Compared to Healthy Controls

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Ingia / Ingia

Background Acute coronary syndrome (ACS) is among the leading causes of death(1). Atherosclerosis and coronary thrombotic occlusion are driven by inflammatory pathomechanisms(2). The investigators have shown neutrophilic activation and neutrophil extracellular traps (NETs) at the culprit lesion site

Resveratrol in Metabolic Syndrome: Effect on Platelet Hyper-reactivity and HDL Lipid Peroxidation

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Ingia / Ingia

Patients with metabolic syndrome are at increased risk of thrombotic complications, including myocardial infarction and cardiovascular death. A meta-analysis of the studies assessing cardiovascular risk in metabolic syndrome found a pooled relative risk for incident cardiovascular events and death

Effects of Chitin-Glucan on Oxidized Low-Density Lipoprotein (LDL)

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Ingia / Ingia

Cardiovascular diseases (CVDs), especially atherosclerotic coronary heart disease and stroke, are the leading causes of death globally. Important risk factors for CVDs include elevated serum levels of total cholesterol, low-density lipoprotein (LDL)-cholesterol, triglycerides, and low high-density

The Effect of Asthma on Systemic Inflammation, Oxidative Stress and Cardiovascular Morbidity

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Ingia / Ingia

Asthma is a chronic inflammatory airway disorder, associated with airflow obstruction and bronchial hyper-responsiveness, which affects about 10% of population in Hong Kong. It has been a major respiratory disease in Hong Kong that carries significant morbidity and high hospitalization burden in all

Use of Beta Blockers in Elderly Trauma Patients

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Ingia / Ingia

Methods of Proposed Research 1. Study Design: Prospective, randomized clinical trial. 2. Study Overview: All trauma patients admitted to the ICU > 55 years of age with a primary diagnosis of injury will be screened on admission as study candidates. Patients will be excluded if they have

A Study of The Effectiveness of N-Acetylcysteine in Kidney Protection Following Cardiopulmonary Bypass

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Ingia / Ingia

Background: N-acetylcysteine (NAC) is an oral or intravenous agent that replenishes glutathione which in turn allows for the formation of glutathione peroxidase, an important enzyme in the degradation cascade of reactive free oxygen radicals. NAC has been shown to reduce recurrent cardiac events in

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