quinine/homa

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Quinine disposition during malaria and during induced fever.

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Ingia / Ingia

Quinine disposition was studied in 5 subjects before and during an experimentally induced infection with a chloroquine-resistant strain of Plasmodium falciparum and in 2 individuals before and during artificially induced fever. Plasma quinine levels were determined by both a benzene extraction

Fever in uncomplicated Plasmodium falciparum infection: effects of quinine and paracetamol.

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Ingia / Ingia

The effects of quinine and paracetamol on fever were studied in 21 adult patients with acute uncomplicated falciparum malaria. Quinine alone (n = 7) had no significant effect on fever, whereas paracetamol given 2 h after quinine (n = 7) or 2 h before quinine (n = 7) reduced temperature by a mean of

The effect of fever on quinine and quinidine disposition in the rat.

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Ingia / Ingia

The pharmacokinetics of quinine and its diastereoisomer quinidine has been investigated in normal and febrile rats. Endotoxin-induced fever in rats resulted in an increased quinine clearance (CL) (4.49 +/- 1.45 vs 1.38 +/- 0.65 L h-1 kg-1, P less than 0.001) and volume of distribution (Vd) (42.6 +/-

CYP450 phenotyping and metabolite identification of quinine by accurate mass UPLC-MS analysis: a possible metabolic link to blackwater fever.

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Ingia / Ingia

BACKGROUND The naturally occurring alkaloid drug, quinine is commonly used for the treatment of severe malaria. Despite centuries of use, its metabolism is still not fully understood, and may play a role in the haemolytic disorders associated with the drug. METHODS Incubations of quinine with CYPs

A Report of Four Cases of Blackwater Fever after Quinine Treatment at Zinder National Hospital, Niger Republic.

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Ingia / Ingia

Blackwater fever (BWF) is a rare but serious complication of malaria that is a consequence of antimalarial treatment. Its prevalence seems to have increased. Its diagnosis is based on clinical symptoms and urine color. We report on 4 BWF cases admitted to the infectious diseases

A study of the anti-pyretic effect of quinine, an alkaloid effective against cerebral malaria, on fever induced by bacterial endotoxin and yeast in rats.

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Ingia / Ingia

The effect of quinine on fever induced by lipopolysaccharide and brewer's yeast has been investigated in rats. Oral administration of 50 or 100 mg kg(-1) quinine, doses which had no effect on normothermic rats, significantly reduced lipopolysaccharide- (50 microg kg(-1), i.m.) and yeast- (2 g

Medicine: Malaria in the Mauritius-The Mosquito and Malaria-The Administration of Quinine, How and When-Anchylostomiasis in St. Lucia-An Effervescing Quinine Mixture-Scurvy and Uric Acid-Experimental Typhoid Fever-Alcohol and Immunity.

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Ingia / Ingia

Special Detailed Report on a Case of Enteric Fever with Remarks on the Influence of Quinine on Temperature.

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Ingia / Ingia

African fever, prophylactic quinine, and statistical analysis: factors in the Europe penetration of a hostile West African environment.

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Ingia / Ingia

A Case of Remittent Fever in a Child Aged Two Years and Nine Months, with an Idiosyncrasy Towards Quinine.

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Ingia / Ingia

A Preliminary Report on the Minimum Curative Dose of Quinine in the Treatment of Malarial Fever by the Intravenous Method.

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Ingia / Ingia

On the External Application of Oil of Turpentine as a Substitute for Quinine in Intermittent Fever, with Reports of Cases.

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Ingia / Ingia

The Treatment of Malarial Fever in Individuals Susceptible to Attacks of Black Water Fever by Intravenous Injection of an Antihæmolytic Quinine Solution.

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Ingia / Ingia

THE DIAGNOSTIC AND PROGNOSTIC VALUE OF THE LEUCOPENIA OF CACHEXIAL FEVER AND KALA-AZAR, AND ITS TREATMENT BY QUININE AND BONE MARROW.

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Ingia / Ingia

Blackwater Fever and Quinine.

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Ingia / Ingia

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