[Qualitative and quantitative assessment of blood erythrocytes of intact animals under the effect of 5-fluorouracil in solution and in microspheres made of acetylcellulose combined with short-term gas hypoxia].

Resistance of erythrocyte membranes, estimated by means of ultrasound hemolysis, was altered 7 days before the cells quantitative changes after simultaneous treatment of intact animals with 5-fluorouracil, administered as solution or in acetate cellulose drug-containing granules, and short-term gas hypoxia. Simultaneous effect of 5-fluorouracil and hypoxia was less toxic for erythropoiesis, while the long-term form of the drug did not affect considerably the liver tissue functions.