Dietary supplement with bilberryshakes 3 times daily for 3 months (containing in total 40g of dried bilberry powder equalling 480 g of fresh berries per day). Product devlopment in collaboration with Glucanova AB.

Dietary supplement with reference shakes 3 times daily for 3 months (containing no active bilberry or no active oats, but with similar texture and taste). Product devlopment in collaboration with Glucanova AB.

Dietary supplement with liquid oat shakes 3 times daily for 3 months (containing beta glucans from the Glucanova® technology, invented by Glucanova AB).Product devlopment in collaboration with Glucanova AB.

Dietary supplement with a combination of liquid oat and bilberry shakes 3 times daily for 3 months. Product devlopment in collaboration with Glucanova AB.

Myocardial Infarction

The dietary intervention will be initiated within 72 hours post PCI and will be continued for three months. After randomization, subjects will be given bilberry shakes (active), liquid oat shakes (active), a combination shake with bilberry and oats, or reference shakes (placebo product containing no active bilberry or active oats but with similar taste and texture), for intake three times a day (t.i.d). The formula for the shakes to be used in the intervention will be finalized during the initial project period.

Bilberry

Placebo

Liquid oats

Combination bilberry/oats

Department of Cardiology, Skånes universitetssjukhus

Cardiology Clinic, Västmanlands sjukhus

Department of Cardiology, Örebro University Hospital

Effects of Dried Bilberry, Liquid Oats, or Their Combination After AMI

Effects of Dried Bilberry, Liquid OAts, or Their Combination, in Patients After Myocardial Infarction. A Randomized, Double-blind, Placebo-controlled Trial (BIOAMI)

The effect of intervention on levels of LDL cholesterol at three months

Fasting lipid profile including HDL, triglycerids, total cholesterol, small-dense LDL cholesterol, apo A, apo B and Lp(a).

The effect of intervention on exercise capacity

The effect of intervention on muscle endurance

The effect of intervention on the Frändin/Grimby activity scale (6 levels of physical activity, min:1 (low activity) max:6 (heavy activity)) and the Haskell physical activity scale ("For how many days were you physically active during the last week for at least 20 minutes?", min:0 max:7)

The effect of intervention on troponin, NT-proBNP, hs_CRP (high sensitivity C-reactive protein), IL-6 and HbA1c (glycosylated hemoglobin).

The effect of intervention on gut microbiome

Insuline, creatinine, Cystatin C, glucose and C-peptide

Ole Frobert, MD, PhD

Professor

Region Västmanland

Region Skane

Chalmers University of Technology

Västerbotten County Council

Atherosclerosis

Hypercholesterolemia

Oat bran

Instituto de Cardiologia do Rio Grande do Sul - Fundação Universitária de Cardiologia

Impact of Consumption of Oats in Lipid Profile of Children and Adolescents With Dyslipidemia

Impact of Consumption of Oats in Lipid Profile of Children and Adolescents With Dyslipidemia at the Outpatient Clinic of Reference in Preventive Pediatric Cardiology at the Institute of Cardiology of Rio Grande do Sul

Impacto do consumo de aveia no perfil lipídico de crianças e adolescentes com dislipidemia atendidas no ambulatório de referência em cardiologia pediátrica preventiva do instituto de cardiologia do rio grande do sul

Instituto de Cardiologia do Rio Grande do Sul

Quaker Oats Company

CNPq Universal

Daily oral dose of 4.5 g of chitin-glucan

Daily oral dose of 1.5 g chitin-glucan + 135 mg olive extract

Cardiovascular

3 x 500 mg capsules (tid) = 4.5 mg daily dose

Chitin-Glucan

3 x 167 mg capsules (tid) = 1.5 g daily dose

Low Dose Chitin-Glucan

3 x 167 mg capsules (tid) = 1.5 g daily dose (C-G) + 135 mg olive extract

Low Dose Chitin-Glucan + Olive Extract

Provident Clinical Research and Consulting

1 3 glucan/enfarktüs

Effects of Dried Bilberry, Liquid Oats, or Their Combination After AMI

Impact of Consumption of Oats in Lipid Profile of Children and Adolescents With Dyslipidemia

Effects of Chitin-Glucan on Oxidized Low-Density Lipoprotein (LDL)

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