The patients will receive 0.9% saline for intravenous bottle with 100ml looks identical to the antibiotic at the start of anesthetic induction

The patients will receive 2 g of cefazolin diluted in 0.9% saline by endovenous at the start of anesthetic induction

Breast Neoplasms

Breast-Conserving Surgery

Wound Infection

Antibiotic Prophylaxis

2 g of cefazolin diluted in 0.9% saline by endovenous, once, at the moment of anesthetic induction

Cefazolin

0.9% saline sterile by endovenous, once, at the moment of anesthetic induction

sterile saline

The patient will be submitted to a conservative oncologic breast surgery

oncologic breast surgery

Samples for quantitative cultures will be obtained in the operating room before antisepsis and the end of surgery. A sample is also collected with the same patterning, on the first postoperative day, immediately after the removal of the dressing placed in the operating room. Will be passed in a standardized manner, a sterile swab soaked in saline over a standard 5cm by 10cm area determined by a field fenestrated sterile filter paper.

Microbiology

Universidade Do Vale Do Sapucai

Antibiotic Prophylaxis in Oncological Surgery of Breast

Antibiotic Prophylaxis in Oncological Surgery of Breast: Randomized Clinical Trial

To evaluate the influence of antibiotic prophylaxis in surgical site infection rates

To evaluate the microbiota that infects the skin in oncological breast surgery

Fabiola Soares Moreira Campos

Department of gynecology

Patients treated with a treatment chosen by sensitivity assay in vitro

Lung Cancer

Colorectal Cancer

Breast Cancer

To test in vitro sensitivity of cancer stem cells to several antineoplastic drugs in order to personalize treatment

Cancer Stem Cells Sensitivity Assay

Department of Medical Oncology

Feasibility Study on Stem Cells Sensitivity Assay

STELLA: a Feasibility Study on Stem Cells Sensitivity Assay

Percentage of patients in which sensitivity assay is feasible

Identification of breast, colo-rectal and lung cancer stem cells by flow cytometric analysis or immunofluorescence

In vitro tumor sensitivity to chemotherapy drugs will be tested on tumor cell cultures per each patient.

agar/meme kanseri

Antibiotic Prophylaxis in Oncological Surgery of Breast

Feasibility Study on Stem Cells Sensitivity Assay

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