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Hyper-IGD syndrome: a new case treated with colchicine.

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We report a new case of hyper-IgD syndrome, a recently described disease characterized by recurrent episodes of fever with headache, bilateral cervical lymphadenopathy and, more rarely, abdominal pain and diarrhoea. Polyclonal increase of serum IgD is the most important laboratory finding.

Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care.

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To compare the effectiveness and safety of naproxen and low-dose colchicine for treating gout flares in primary care.This was a multicentre open-label randomised trial. Adults with a gout flare recruited from 100 general practices were randomised equally to

[A case of Behçet disease with transverse sinus thrombosis and successful treatment with colchicine].

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A 64-year-old man was admitted to our hospital because of headache and fever. Four months before admission, he had suffered from thrombophlebitis of the legs, erythema, oral aphtha and genital ulcers, and was diagnosed as having Behçet disease. Several days prior to admission he developed fever and

Effect of anti-interleukin-1 treatment on quality of life in children with colchicine-resistant familial Mediterranean fever: A single-center experience

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Aim: The aim of this study is to evaluate the clinical parameters, acute-phase reactants, side effects, genetic mutations among colchicine-resistant Familial Mediterranean fever (FMF) patients who received anti-interleukin-1 (anti-IL-1)

Activity of botulinum toxin type A in cranial dura: implications for treatment of migraine and other headaches.

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OBJECTIVE Although botulinum toxin type A (BoNT/A) is approved for chronic migraine treatment, its mechanism of action is still unknown. Dural neurogenic inflammation (DNI) commonly used to investigate migraine pathophysiology can be evoked by trigeminal pain. Here, we investigated the reactivity of

[Colchicine: a potential therapeutic tool against COVID-19. Experience of 5 patients]

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COVID-19 is a newly emerged disease that has become a global public health challenge. Due to a lack of knowledge about the virus, a significant number of potential targets for using a particular drug have been proposed. Five cases with a clinical history of biopolymers in the gluteal region that

Cyclosporine for Behçet's uveitis: is it associated with an increased risk of neurological involvement?

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OBJECTIVE The immunosuppressant cyclosporine is widely used to treat Behçet's disease (BD). The aim of this study was to determine whether cyclosporine increases the risk of neurological involvement in BD. METHODS Patient files from the Ophthalmology Department for the period 2000-2005 were screened

[Intracranial primary malignant lymphoma following Behçet's disease--case report].

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We reported a case of intracranial primary malignant lymphoma following Behçet disease treated with colchicine. A 43-year-old female with a past history of oral ulcer and folliculitis visited the Department of Ophthalmology on December, 1990, because of her impaired visual acuity. A diagnosis of

Optic nerve involvement in neuro-Behcet's disease.

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BACKGROUND To report the ocular manifestations of neuro-Behcet's disease. METHODS A 34-year-old woman had recurrent meningitis. She developed diplopia, headache, and ataxia, and was diagnosed as having neuro-Behcet's disease. METHODS Imaging revealed two infarct foci in the transitional midbrain and

Atypical Presentation of Acute Myeloid Leukemia.

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We present a case of a 48-year-old male who presented with worsening pleuritic chest pain for 2 h. He also complained of fever, malaise, headache and severe neck pain. Electrocardiogram (ECG) showed ST segment elevation in leads I, II, aVL and V5 with PR elevation and ST depression in aVR. On

Clinical characteristics of paediatric neuro-Behçet's disease: a single tertiary centre experience.

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OBJECTIVE To investigate the demographic and neurological features and treatment modalities of neuro-Behçet's disease (NBD) in children, to share our experiences and to summarise the literature. METHODS We retrospectively reviewed the medical records of Behçet's disease (BD) patients who attended

Drug reactions in children with rheumatic diseases receiving parenteral therapies: 9 years' experience of a tertiary pediatric rheumatology center.

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Parenteral treatments (either subcutaneous or intravenous) are frequently used in rheumatology practice. In this study, drug side effects in patients who were followed up with a rheumatic disease and treated with parenteral administration methods were evaluated. The drug side effects in children who

Crowned dens syndrome misdiagnosed as polymyalgia rheumatica, giant cell arteritis, meningitis or spondylitis: an analysis of eight cases.

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BACKGROUND The crowned dens syndrome, related to microcrystalline deposition in the peri-odontoid articular and abarticular structures, is mainly responsible for acute or chronic cervical pain. METHODS We report eight cases of crowned dens syndrome with atypical presentations mimicking giant cell

Eighteen cases of crowned dens syndrome: Presentation and diagnosis.

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OBJECTIVE Crowned dens syndrome is an ill-known etiology of acute neck pain. METHODS We carried out a retrospective study of 18 cases of patients with crowned dens syndrome, assessing clinical and radiological features. RESULTS The results of our study are comparable to data from the literature. The

Neuro-Behçet's disease in childhood: a focus on the neuro-ophthalmological features.

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Neuro-Behçet's disease (NBD) involves the central nervous system; peripheral nervous system involvement is not often reported. NBD is quite common in adult patients and occurs rarely during childhood and adolescence. Young patients may share symptoms and signs of NBD with other

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