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cystic fibrosis/ödem

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P.sup.1-(2'-deoxycytidine 5'-)P.sup.4-(uridine 5'-)tetraphosphate, tetra-(alkali metal) salt, for treating cystic fibrosis

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TECHNICAL FIELD This invention relates to a method of treating edematous retinal disorders. Specifically, this invention relates to a method of removing pathological fluid accumulation in subretinal and intra-retinal spaces. This invention also relates to dinucleoside polyphosphate salts, such as a

Method for treating pulmonary diseases using rho kinase inhibitor compounds

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TECHNICAL FIELD This invention relates to methods of preventing or treating diseases or conditions of the lung associated with excessive cell proliferation, remodeling, inflammation, vasoconstriction, bronchoconstriction, airway hyperreactivity and edema. Particularly, this invention relates to

Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use

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This application is related to, not a continuing case to U.S. Pat. Nos. 6,172,060, 6,197,778, 6,177,428, 6,172,068, 6,221,881, 6,232,321, 6,197,782, 6,133,272, and 6,211,179. FIELD OF THE INVENTION The present invention describes novel nitrosated and/or nitrosylated phosphodiesterase inhibitors, and

Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use

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FIELD OF THE INVENTION The present invention describes novel nitrosated and/or nitrosylated phosphodiesterase inhibitors, and novel compositions comprising at least one nitrosated and/or nitrosylated phosphodiesterase inhibitor, and, optionally, at least one compound that donates, transfers or

Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use

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FIELD OF THE INVENTION The present invention describes novel nitrosated and/or nitrosylated phosphodiesterase inhibitors, and novel compositions comprising at least one nitrosated and/or nitrosylated phosphodiesterase inhibitor, and, optionally, at least one compound that donates, transfers or

Methods of treating pulmonary disease using acetazolamide and structurally related derivatives

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FIELD OF THE INVENTION The present invention relates to methods of treating pulmonary disease using acetazolamide and structurally related derivatives. BACKGROUND OF THE INVENTION Alveolar hypoxia, as occurs with ascent to high altitude or chronic lung diseases, results in hypoxic pulmonary

Deuterium-enriched pyrimidine compounds and derivatives

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FIELD OF THE INVENTION The invention generally relates to the field of deuterium-enriched pyrimidine compounds, their derivatives, enantiomers, diasteromers, solvates and pharmaceutical salts thereof for the treatment, prevention and potential cure of various diseases including chronic liver

Substituted saturated aza heterocycles as inhibitors of nitric oxide synthase

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CROSS REFERENCE TO RELATED APPLICATION The present invention is based on, and claims priority from 60/008,390, filed Dec. 8, 1995. BACKGROUND OF THE INVENTION This application is directed to inhibitors of nitric oxide synthase, and in particular substituted azacycle derivatives. Nitric Oxide in

Cyclic amidine analogs as inhibitors of nitric oxide synthase

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BACKGROUND OF THE INVENTION This application is directed to inhibitors of Nitric oxide synthase, and in particular cyclic amidines. Nitric Oxide in Biology. The emergence of nitric oxide (NO), a reactive, inorganic radical gas as a molecule contributing to important physiological and pathological
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