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fibrosis/seizures

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Use of isatin derivatives as ion channel activating agents

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TECHNICAL FIELD The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SK.sub.Ca and IK.sub.Ca channels. In further aspects, the present invention relates to the

Substituted [1,2,4]triazolo[4,3-a]pyrazines as P2X7 modulators

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CROSS REFERENCE TO RELATED APPLICATIONS This application is a national phase of International Application No. PCT/US2014/027450 filed on Mar. 14, 2014, which claims the benefit of U.S. Provisional Application No. 61/785,478 filed on Mar. 14, 2013, each of which are incorporated herein by reference

Potassium channel blocking agents

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TECHNICAL FIELD This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions. Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the

Bis (benzimidazole) derivatives serving as potassium blocking agents

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TECHNICAL FIELD This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions. Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the

Bis(benzimidazole) derivatives serving as potassium blocking agents

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TECHNICAL FIELD This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions. Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the

Beta-casein A2 and antioxidant capacity

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TECHNICAL FIELD The invention relates to the milk protein A2 beta-casein and improving the antioxidant capacity in an animal by increasing the levels of glutathione in the body of the animal. In particular, the invention relates to milk and milk derived food products. The applicant has found that

Substituted saturated aza heterocycles as inhibitors of nitric oxide synthase

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CROSS REFERENCE TO RELATED APPLICATION The present invention is based on, and claims priority from 60/008,390, filed Dec. 8, 1995. BACKGROUND OF THE INVENTION This application is directed to inhibitors of nitric oxide synthase, and in particular substituted azacycle derivatives. Nitric Oxide in

Cyclic amidine analogs as inhibitors of nitric oxide synthase

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BACKGROUND OF THE INVENTION This application is directed to inhibitors of Nitric oxide synthase, and in particular cyclic amidines. Nitric Oxide in Biology. The emergence of nitric oxide (NO), a reactive, inorganic radical gas as a molecule contributing to important physiological and pathological
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