Hyperplasia / tyrosine

Tyrosine kinase inhibitors

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BACKGROUND OF THE INVENTION This invention relates to salt forms of the compound N-[(2R)-1,4-dioxan-2-ylmethyl]-N-methyl-N'-[3-(1-methyl-1H-pyrazol-4-yl)-- 5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]sulfamide, an inhibitor of tyrosine kinases, in particular the receptor tyrosine kinase MET,

Altered intracellular localization of BRK/Sik protein tyrosine kinase in human prostate tumors

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FIELD OF THE INVENTION The invention relates to methods for detecting an abnormal prostate condition in an animal. Specifically, the invention relates to methods of detecting an abnormal prostate condition in an animal by detecting the amount of Breast Tumor Kinase (BRK) protein present in the

Catheter device and method of use for intramural delivery of protein kinase C and tyrosine protein kinase inhibitors to prevent restenosis after balloon angioplasty

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This invention relates generally to the medical and veterinary medical field of atherosclerotic lesion treatment. More particularly, this invention relates to a catheter device and a method for the local delivery into the vessel wall of specific inhibitors of protein kinase C (PKC) and tyrosine

Fumaric acid salt of 9-[4-(3-chloro-2-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-1,4-di- aza-spiro[5.5]undecan-5-one, its use as a medicament and the preparation thereof

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The present invention relates to the compound of formula (I), ##STR00002## which has valuable pharmacological properties, particularly an inhibiting effect on signal transduction mediated by tyrosine kinases, processes for stereoselectively preparing this compound, particularly pharmaceutical

9-[4-(3-chloro-2-fluoro-phenylamino)-7-methoxy-quinazoline-6-yloxy]-1,4-di- aza-spiro[5.5] undecane-5-one dimaleate, use thereof as a medicament and method for the production thereof

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The present invention relates to the compound of formula (I), ##STR00002## which has valuable pharmacological properties, particularly an inhibiting effect on signal transduction mediated by tyrosine kinases, processes for stereoselectively preparing this compound, particularly pharmaceutical

9-[4-(3-chloro-2-fluoro-phenylamino-7-methoxy-quinazoline-6-yloxy]-1,4-dia- za-spiro[5.5]undecane-5-one dimaleate, use thereof as a medicament and method for the production thereof

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The present invention relates to the compound of formula (I), ##STR00002## which has valuable pharmacological properties, particularly an inhibiting effect on signal transduction mediated by tyrosine kinases, processes for stereoselectively preparing this compound, particularly pharmaceutical

Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation

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FIELD OF THE INVENTION The present invention relates to bicyclic heterocycles of the general formula ##STR00002## their tautomers, their stereoisomers, their mixtures and their salts, in particular their physiologically tolerable salts with inorganic or organic acids, which have valuable

Bicyclic heterocycles, medicaments containing said compounds, use thereof, and method for production of same

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This application is the national phase entry under 35 U.S.C. .sctn.371 of International Application No. PCT/EP2007/061842, filed Nov. 3, 2007, which claims priority to European Application No. 06123820.0, filed Nov. 10, 2006, each of which is hereby incorporated by reference in its entirety. The

Spirocyclic heterocycles medicaments containing said compounds, use thereof and method for their production

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The present invention relates to spirocyclic heterocycles of general formula ##STR00002## the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids, which have valuable pharmacological

Spirocyclic heterocycles medicaments containing said compounds, use thereof and method for their production

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The present invention relates to spirocyclic heterocycles of general formula ##STR00002## the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids, which have valuable pharmacological

Cyclohexyloxy-substituted heterocyclics, medicines containing these compounds and method for the production thereof

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The present invention relates to cyclohexyloxy-substituted heterocycles of general formula ##STR00002## the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids, which have valuable

Cyclohexyloxy substituted heterocycles, pharmaceutical compositions containing these compounds and processes for preparing them

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The present invention relates to cyclohexyloxy-substituted heterocycles of general formula ##STR00002## the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids, which have valuable

Bicyclic heterocycles, drugs containing said compounds, use thereof, and method for production thereof

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This application is the national phase entry under 35 U.S.C. .sctn.371 of International Application No. PCT/EP2008/051141, filed Jan. 30, 2008, which claims priority to European Application No. 07101785.9, filed Feb. 6, 2007, and European Application No. 07118700.9, filed Oct. 17, 2007, each of

Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them

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The present invention relates to bicyclic heterocycles of general formula ##STR00002## the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids which have valuable pharmacological

Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them

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The present invention relates to bicyclic heterocycles of general formula ##STR00002## the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids, which have valuable pharmacological

hyperplasia/tyrosine

Tyrosine kinase inhibitors

Altered intracellular localization of BRK/Sik protein tyrosine kinase in human prostate tumors

Catheter device and method of use for intramural delivery of protein kinase C and tyrosine protein kinase inhibitors to prevent restenosis after balloon angioplasty

Fumaric acid salt of 9-[4-(3-chloro-2-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-1,4-di- aza-spiro[5.5]undecan-5-one, its use as a medicament and the preparation thereof

9-[4-(3-chloro-2-fluoro-phenylamino)-7-methoxy-quinazoline-6-yloxy]-1,4-di- aza-spiro[5.5] undecane-5-one dimaleate, use thereof as a medicament and method for the production thereof

9-[4-(3-chloro-2-fluoro-phenylamino-7-methoxy-quinazoline-6-yloxy]-1,4-dia- za-spiro[5.5]undecane-5-one dimaleate, use thereof as a medicament and method for the production thereof

Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation

Bicyclic heterocycles, medicaments containing said compounds, use thereof, and method for production of same

Spirocyclic heterocycles medicaments containing said compounds, use thereof and method for their production

Spirocyclic heterocycles medicaments containing said compounds, use thereof and method for their production

Cyclohexyloxy-substituted heterocyclics, medicines containing these compounds and method for the production thereof

Cyclohexyloxy substituted heterocycles, pharmaceutical compositions containing these compounds and processes for preparing them

Bicyclic heterocycles, drugs containing said compounds, use thereof, and method for production thereof

Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them

Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them

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