hyperthyroidism/phosphatase

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Tissue sources of serum alkaline phosphatase in 34 hyperthyroid cats: a qualitative and quantitative study.

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The concentration of serum alkaline phosphatase (SALP) is commonly elevated in hyperthyroid cats. Agarose gel electrophoresis, in tris -barbital-sodium barbital buffer, with and without the separation enhancer neuraminidase, was used to investigate the sources of the constituent isoenzymes of SALP

[Alkaline phosphatase isoenzymes and hyperthyroidism].

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We determined the serum total alkaline phosphatase as well as the alkaline phosphatase isoenzyme pattern in untreated and treated hyperthyreoses in the condition of euthyreosis and compared them with those of a healthy control group. The isoenzyme patterns, expressed as L/K quotient, ranged between

Alkaline phosphatase isoenzyme patterns in hyperthyroidism.

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Fifteen of 36 hyperthyroid patients had elevation in serum alkaline phosphatase activity. There was no difference in mean thyroxine (T4), triiodothyronine (T3), age, or duration of illness between the groups with high alkaline phosphatase and normal alkaline phosphatase levels. After treatment,

Stimulation of alkaline phosphatase activity by thyroid hormone in mouse osteoblast-like cells (MC3T3-E1): a possible mechanism of hyperalkaline phosphatasia in hyperthyroidism.

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In order to elucidate the mechanism of increased alkaline phosphatase (AI-P) activity of bone origin in serum of patients with hyperthyroidism, the effects of thyroid hormone on mouse osteoblast-like cells (MC3T3-E1) were studied in vitro. Triiodo-L-thyronine (T3) and thyroxine (T4) produced a

Low-frequency stimulation induces a durable long-term depression in young adult hyperthyroid rats: the role of p38 mitogen-activated protein kinase and protein phosphatase 1.

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Long-term potentiation and long-term depression (LTD) are cellular mechanisms of learning and memory in the mammalian brain. We have previously shown that adult hyperthyroid rats showed a delay in the acquisition of a place learning task and attenuated long-term potentiation. However, changes in LTD

Plasma 25-hydroxyvitamin D and alkaline phosphatase isoenzymes in hyperthyroidism.

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Plasma 25-hydroxyvitamin D (25-OHD) values in 22 hyperthyroid patients did not differ significantly from those of controls matched for age, sex, and the time of year that plasma samples were taken. In the hyperthyroid group, plasma alkaline phosphatase was significantly higher than in controls, and

Agarose gel electrophoresis of alkaline phosphatase isoenzymes in the serum of hyperthyroid cats.

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Cats with hyperthyroidism [(increased serum thyroxine (T(4))] commonly have increased serum alkaline phosphatase (ALP) activity in addition to other serum biochemical abnormalities. Serum biochemical profiles were obtained from 10 hyperthyroid cats which had increased serum ALP. Agarose gel

Tissue sources of elevated serum alkaline phosphatase activity in hyperthyroid patients.

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Total alkaline phosphatase (ALP) and its isoenzymes were studied in the sera of 72 hyperthyroid patients and 24 age- and sex-matched controls. Eighty-nine per cent of thyrotoxic patients had elevated total serum ALP activity. Both liver (LALP) and bone (BALP) isoenzymes were present in the sera of

Alkaline phosphatase isoenzymes in plasma in hyperthyroidism.

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Alkaline phosphatase (ALP; EC 3.1.3.1) isoenzymes were measured in the plasma of 63 untreated hyperthyroid patients (the hyperthyroid group), 58 treated hyperthyroid patients, and 100 blood donors. Total, liver, and bone ALP activities were significantly higher in the hyperthyroid group than in the

[Serum levels of the tartrate-resistant isoenzyme, acid phosphatase, for the evaluation of bone remodeling in hyperthyroidism].

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Tartrate-resistant acid phosphatase (TRAP) is one of the acid phosphatase isoenzymes. It is secreted by osteoclasts so it has been proposed as a marker of bone resorption. Bone turnover is high in hyperthyroidism due to an increase in both bone resorption and formation. The aim of the study was to

Alkaline phosphatase bone isoenzyme and osteocalcin in the serum of hyperthyroid cats.

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The effect of hyperthyroidism on serum markers for increased bone metabolism and turnover was evaluated in 36 cats with elevated serum levels of thyroxine and alkaline phosphatase. Serum was analyzed for total and ionized calcium and phosphorous. Alkaline phosphatase isoenzymes were separated by

Leukocyte alkaline phosphatase in hypothyroidism and hyperthyroidism. Response to initiation of thyroxine replacement therapy.

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Leukocyte alkaline phosphatase (LAP) activity was determined in normal subjects, and in untreated, symptomatic patients with primary hypothyroidism or thyrotoxicosis. The means +/- 1 SD of (n) subjects were, respectively: 61.7 +/- 27.5 (16), 149.9 +/- 56.3 (9) and 96.9 +/- 27.7 (9). The mean LAP

[A histochemical study of gastric adenosine triphosphatase, alkaline and acid phosphatase in experimental hypo- and hyperthyroidism].

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[Changes in the activity of granulocytic alkaline phosphatase after surgical treatment of hyperthyroidism with respect to other deviations in the white corpuscles system].

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[An increase in alkaline phosphatases: an approach to the diagnosis of hyperthyroidism].

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