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hypertriglyceridemia/tyrosine

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Protein tyrosine phosphatase inhibitors and methods of use thereof

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FIELD OF THE INVENTION This invention relates to the field of protein tyrosine phosphatase inhibition. BACKGROUND OF THE INVENTION This invention relates to a novel class of phosphonic acid derivatives that are inhibitors of PTP-1B. Reversible protein tyrosine phosphorylation, coordinated by the

Protein tyrosine phosphatase inhibitors and methods of use thereof

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FIELD OF THE INVENTION This invention relates to the field of protein tyrosine phosphatase inhibition. BACKGROUND OF THE INVENTION This invention relates to a novel class of phosphonic acid derivatives that are inhibitors of PTP-1B. Reversible protein tyrosine phosphorylation, coordinated by the

1,2,5-thiazolidine derivatives useful for treating conditions mediated by protein tyrosine phosphatases (PTPase)

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This application is the National Stage of Application No. PCT/EP2006/046543, filed on Dec. 6, 2006, which claims benefit under 35 U.S.C. .sctn.119(a-d) of U.S. Provisional Application No. 60/748,491, filed Dec. 8, 2005, the contents of which are incorporated herein by reference in their

Oxindole hydrazide modulators of protein tyrosine phosphatases (PTPs)

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FIELD OF THE INVENTION The present invention is related to the use of oxindole hydrazide derivatives of formula (I) for the treatment and/or prevention of metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type I and/or II, inadequate glucose tolerance, insulin

Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases (PTPs)

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FIELD OF THE INVENTION The present invention is related to substituted methylene amide derivatives of formula (I), in particular for the treatment and/or prevention of metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type I and/or II, inadequate glucose

1-orthofluorophenyl substituted 1,2,5-thiazolidinedione derivatives as PTP-as inhibitors

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The present invention relates to thiadiazolidinone derivatives, pharmaceutical compositions containing such compounds, methods of making such and methods of treating conditions mediated by protein tyrosine phosphatases by employing such compounds. Accordingly, the present invention provides

Organic compounds

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The present invention relates to thiadiazolidinone derivatives, pharmaceutical compositions containing such compounds, methods of making such and methods of treating conditions mediated by protein tyrosine phosphatases by employing such compounds. Accordingly, the present invention provides
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