hypothyroidism/phosphatase

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Leukocyte alkaline phosphatase in hypothyroidism and hyperthyroidism. Response to initiation of thyroxine replacement therapy.

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Leukocyte alkaline phosphatase (LAP) activity was determined in normal subjects, and in untreated, symptomatic patients with primary hypothyroidism or thyrotoxicosis. The means +/- 1 SD of (n) subjects were, respectively: 61.7 +/- 27.5 (16), 149.9 +/- 56.3 (9) and 96.9 +/- 27.7 (9). The mean LAP

[Determination of changes in serum cholesterol and alkaline phosphatase levels in the diagnosis and during treatment of hypothyroidism in children].

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[Histochemistry of phosphatases in the pituitary in rats in experimental hypothyroidism].

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[Blast transformation and the activity of acid phosphatase of circulating lymphocytes in experimental hypothyroidism].

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Decreased serum alkaline phosphatase activity in hypothyroidism: possible relationship to low serum zinc and magnesium.

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Hypothyroidism has an adverse effect on human spermatogenesis: a prospective, controlled study.

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BACKGROUND Abnormalities of spermatogenesis are associated with numerous diseases and aging. The objective of this study was to investigate the impact of hypothyroidism on human spermatogenesis and different sperm function tests. METHODS Twenty-five hypothyroid men and 15 normal individuals were

Effect of methimazole-induced hypothyroidism on alveolar macrophages.

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Chemically induced hypothyroidism changes the functions of rat alveolar macrophages. Treatment of female rats with an anti-thyroid drug, methimazole (1% aqueous solution in drinking water for 6 weeks) significantly (p less than 0.05) reduced the ability of alveolar macrophages (MAM) to phagocytose

[Study of bone involvement in hypothyroidism determining the blood levels of osteocalcin].

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Several bone abnormalities, characterized by a decreased bone turnover, may develop in patients with hypothyroidism. We have used the measurement of serum Osteocalcin (BGP), a protein synthesized by osteoblasts and proposed as a marker of bone formation, in order to elucidate the bone status in 62

Effect on renal function of restoration of euthyroidism in hyperthyroid cats with iatrogenic hypothyroidism.

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BACKGROUND Iatrogenic hypothyroidism is associated with an increased incidence of azotemia after treatment of hyperthyroidism, and decreased survival time in azotemic hyperthyroid cats. OBJECTIVE Restoration of euthyroidism will decrease plasma creatinine concentrations. METHODS Nineteen

Increased sensitivity to thyroid hormone replacement therapy followed by hyponatremia and eosinophilia in a patient with long-standing young-onset primary hypothyroidism.

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We describe a 51-year-old woman with long-standing young-onset primary hypothyroidism. Serum cortisol, adrenocorticotropin, and arginine vasopressin levels were normal, but urinary excretion of 17-hydroxycorticosteroid was decreased. Administration of a very small initial dose of thyroid hormone

Lessons to be learned: a case study approach: severe hyponatraemia induced by primary hypothyroidism and associated with possible increased hepatic sensitivity to thyroxine replacement.

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The case is presented of a 74 year-old woman who was admitted with severe hypo-osmolar hyponatraemia associated with inappropriately raised urinary osmolality, and who was subsequently discovered to have primary hypothyroidism. A normal serum sodium concentration was restored by means of judicious

A case of congenital nephrotic syndrome associated with partial deficiency of lecithin cholesterol acyltransferase (LCAT) and hypothyroidism.

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The case of a 3 year-old boy with congenital nephrotic syndrome is reported, in whom decreased LCAT activity and hypothyroidism were also present. Renal biopsy confirmed a diffuse proliferative glomerulonephritis with a large number of foam cells in the capillary lumen of the glomerulus and the

Hepatic dysfunction in primary hypothyroidism.

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Twenty-seven patients with primary hypothyroidism were studied to evaluate the relationship between hepatic function and thyroid hormone deficiency in this disorder. In hypothyroidism, hypergammaglobulinemia was found in 71%, elevated glutamic oxaloacetic transaminase (GOT) in 48%, high lactic

[The replacement therapy of rPTH(1-84) in established rat model of hypothyroidism].

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OBJECTIVE To investigate the replacement therapy of rPTH(1-84) (recombinant human parathyroid hormone (1-84)) to hypothyroidism in established rat model. METHODS Rat model of hypothyroidism was established by resecting parathyroids. A total of 30 rats with removal of parathyroids were divided into 6

Early changes in parameters of bone and mineral metabolism during therapy for hyper- and hypothyroidism.

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The effects of thyroid hormones on various organs and metabolic systems have been the focus of intensive research. In this study we investigated the mechanisms of the changes in some parameters of bone and mineral metabolism before and during treatment of hyper- and hypothyroidism. Our study groups

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