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The use of cannabis and perceptions of its effect on fertility among infertility patients.

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What is the prevalence of cannabis use and the perceptions of its impact on fertility among infertility patients?A total of 13% of infertility patients used cannabis within the last year, and current usage is associated with patient perceptions of negative

Marijuana smoking and outcomes of infertility treatment with assisted reproductive technologies.

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What is the association of female and male partner marijuana smoking with infertility treatment outcomes with ART?Women who were marijuana smokers at enrollment had a significantly higher adjusted probability of pregnancy loss during infertility treatment

The relationship between cannabis and male infertility, sexual health, and neoplasm: a systematic review.

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In the United States of America (USA), cannabis is legal in 28 states for medical purposes and 8 states for recreational use. In 2016, the legal marijuana industry reached nearly $7 billion in sales in the USA alone. Although consumption continues to increase, the medical effects of

[Female sterility in hemp (Cannabis sativa L.)].

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Type-1 cannabinoid receptors reduce membrane fluidity of capacitated boar sperm by impairing their activation by bicarbonate.

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BACKGROUND Mammalian spermatozoa acquire their full fertilizing ability (so called capacitation) within the female genital tract, where they are progressively exposed to inverse gradients of inhibiting and stimulating molecules. RESULTS In the present research, the effect on this process of

Expression and localization of cannabinoid receptors in human immature oocytes and unfertilized metaphase-II oocytes.

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Endocannabinoid anandamide and cannabinoid receptors have been described in some organs of the female reproductive system, but little is known about the expression of these receptors in human oocytes. The aim of the study was to describe the expression of cannabinoid receptors in human oocytes and

Fertility and use of cigarettes, alcohol, marijuana, and cocaine.

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This study demonstrated that cigarette smoking was associated with an increase in both time to conception (among 2817 fertile women) and risk of primary infertility (among 1818 infertile women and their primiparous control subjects). The average time to conception was 4.3 months for women who never

Cannabis consumption might exert deleterious effects on sperm nuclear quality in infertile men.

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Can cannabis consumption alter sperm nuclear integrity in infertile men?A retrospective cross-sectional study conducted between July 2003 and December 2013, which included 54 men who consulted for male-factor infertility. Twenty-seven infertile men who were

Mutagenicity, developmental toxicity and carcinogenicity of cannabis.

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Data on the mutagenicity, developmental toxicity and carcinogenicity of cannabis are reviewed in this article. The available evidence on the possible mutagenic effects of cannabinoids is still inconclusive. There is no consensus on the induction of point mutations, while some experimental results

Spatial distribution of cannabinoid receptor 1 and fatty acid amide hydrolase in the cat ovary and oviduct.

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Involvement of the endocannabinoid system in female reproduction has been extensively described in humans with the cognate receptors and ligands being found in the ovaries and genital tract. In human, an imbalance of the endocannabinoid system is linked with both ectopic pregnancy and infertility.

The (endo)cannabinoid signaling in female reproduction: What are the latest advances?

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Cannabis extracts like marijuana have the highest consumption rate worldwide. Yet, their societal acceptance as recreational and therapeutic drugs could represent a serious hazard to female human reproduction, because cannabis ingredients [termed (phyto)cannabinoids] can perturb an endogenous system

The effects of cannabinoids on the endocrine system.

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Cannabinoids are the derivatives of the cannabis plant, the most potent bioactive component of which is tetrahydrocannabinol (THC). The most commonly used drugs containing cannabinoids are marijuana, hashish, and hashish oil. These compounds exert their effects via interaction with the cannabinoid

Melatonin and vitamin C exacerbate Cannabis sativa-induced testicular damage when administered separately but ameliorate it when combined in rats.

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BACKGROUND The mechanisms involved in the spermatotoxic effect of Cannabis sativa are inconclusive. The involvement of oxidative stress in male factor infertility has been well documented, and the antioxidative potential of melatonin and vitamin C in many oxidative stress conditions has been well

Regulation of gonadotropin-releasing hormone secretion by cannabinoids.

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Cannabinoids (CBs) exert untoward effects on reproduction by reducing LH secretion and suppressing gonadal function. Recent evidence suggests these effects are due primarily to hypothalamic dysfunction; however, the mechanism is obscure. Using immortalized hypothalamic GnRH neurons, we find these

Cannabis and Male Fertility: A Systematic Review.

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With cannabis consumption on the rise, and use prominent among males of reproductive age, it is essential to understand the potential impact of cannabis on male fertility. Here we review the literature regarding cannabis' effects on male fertility.A

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