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insulin resistance/obezite

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Sayfa 1 itibaren 467 Sonuçlar
CROSS-REFERENCE TO RELATED APPLICATIONS This application is the U.S. national stage filing under 35 U.S.C. .sctn.371 of international application PCT/KR2010/008944, filed Dec. 14, 2010, which claims benefit of Korean Patent Application No. 10-2010-0004901, filed Jan. 19, 2010. FIELD OF THE

Method for treatment of obesity, dyslipidemia, fatty liver or insulin resistance syndrome comprising camphene as active ingredient

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CROSS-REFERENCE TO RELATED APPLICATIONS This application is the U.S. national stage filing under 35 U.S.C. .sctn.371 of international application PCT/KR2009/007905, filed Dec. 29, 2009, which claims benefit of Korean Patent Application 10-2009-0022937, filed Mar. 18, 2009. TECHNICAL FIELD The
CROSS-REFERENCE TO RELATED APPLICATIONS This application is the U.S. national stage filing under 35 U.S.C. .sctn.371 of international application PCT/KR2010/008206, filed Nov. 19, 2010, which claims priority from Korea Patent Application 10-2010-0041249, filed May 3, 2010. BACKGROUND OF THE

Compositions for treating obesity and insulin resistance disorders

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BACKGROUND Obesity is a chronic condition that is characterized by a body mass index (BMI) over 25. Both congenital and environmental factors, such as exercise and eating habits, contribute to the disease. For instance, the hormone leptin has been shown to be involved in fat accumulation and

Compositions for treating obesity and insulin resistance disorders

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Giriş yapmak kayıt olmak
BACKGROUND Obesity is a chronic condition that is characterized by a body mass index (BMI) over 25. Both congenital and environmental factors, such as exercise and eating habits, contribute to the disease. For instance, the hormone leptin has been shown to be involved in fat accumulation and

Compositions for treating obesity and insulin resistance disorders

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Giriş yapmak kayıt olmak
BACKGROUND Obesity is a chronic condition that is characterized by a body mass index (BMI) over 25. Both congenital and environmental factors, such as exercise and eating habits, contribute to the disease. For instance, the hormone leptin has been shown to be involved in fat accumulation and

Method for treatment of insulin resistance in obesity and diabetes

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FIELD OF THE INVENTION The present invention relates to a non-human animal model for obesity and uses of such an animal for studying and developing methods for identifying compounds for use in the regulation of insulin resistance in obesity and type II diabetes, as well as a method of treating

Regulators of PPAR.delta. (.beta.) and their use in the treatment of obesity and insulin resistance

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FIELD OF THE INVENTION The present invention relates to a method for treating obesity, insulin resistance and dyslipidemia in mammals including humans through inhibition of PPAR.delta.(.beta.). This invention also relates to methods of screening for chemical entities that act to regulate

Treatment of insulin resistance in obesity linked type II diabetes using antagonists to TNF-.alpha. function

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BACKGROUND OF THE INVENTION Obesity and diabetes are among the most common human health problems in industrialized societies. Obesity, which is the result of an imbalance between caloric intake and energy expenditure, is highly correlated with insulin resistance and diabetes in experimental animals

Treatment of insulin resistance in obesity linked type II diabetes using antagonist to TNF-alpha function

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BACKGROUND OF THE INVENTION Obesity and diabetes are among the most common human health problems in industrialized societies. Obesity, which is the result of an imbalance between caloric intake and energy expenditure, is highly correlated with insulin resistance and diabetes in experimental animals

CD36 inhibition to control obesity and insulin sensitivity

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BACKGROUND CD36 is a multifunctional receptor that is expressed in various types of cells and tissues including brain microglia and astrocytes as well as monocytes/macrophages and adipocytes. CD36 recognizes many ligands including oxidized or modified low density lipoprotein (oxLDL, mLDL),

RBP4 in insulin sensitivity/resistance, diabetes, and obesity

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BACKGROUND OF THE INVENTION Insulin resistance in the peripheral tissues such as muscle and fat is associated with increased secretion of insulin by pancreatic .beta.-cells. The secreted insulin promotes glucose utilization and inhibits production of glucose by the liver. However, the pancreatic

RBP4 in insulin sensitivity/resistance, diabetes, and obesity

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BACKGROUND OF THE INVENTION Insulin resistance in the peripheral tissues such as muscle and fat is associated with increased secretion of insulin by pancreatic .beta.-cells. The secreted insulin promotes glucose utilization and inhibits production of glucose by the liver. However, the pancreatic

RBP4 in insulin sensitivity/resistance, diabetes, and obesity

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BACKGROUND OF THE INVENTION Insulin resistance in the peripheral tissues such as muscle and fat is associated with increased secretion of insulin by pancreatic .beta.-cells. The secreted insulin promotes glucose utilization and inhibits production of glucose by the liver. However, the pancreatic
The present invention relates to the use of ketoconazole or molecules resembling ketoconazole but with some side-chains, not affecting the biological activity compared to ketoconazole, changed for manufacturing drugs for treatment of diabetes mellitus type II. The drug ketoconazole (e.g., under the
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