uric acid/enflamasyon

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Prebiotic Therapy to Improve Outcomes of Renal Transplant

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Nearly three million people worldwide suffer from end stage renal disease (ESRD), which has debilitating consequences on the quality of life of patients There is a discrepancy between the availability of organs and the increasing number of patients placed on the waiting list. Canadians with ESRD

Effect of Oxalate and Urate Metabolism on CKD Evolution

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The study protocol is approved by a local Ethics Committee and registered in Domestic Clinical Trial Registry (Identifier 0119U000002). Writing informed consent is obtained from all subjects participating in the study. The study will enroll 300 participants (250 CKD patients at stage 1-5 and 50

A Phase II, Controlled Clinical Study Designed to Evaluate the Effect of ArtemiC in Patients Diagnosed With COVID-19

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STUDY OBJECTIVES This study is designed to evaluate the safety and efficacy of ArtemiC on patients diagnosed with COVID-19. STUDY TREATMENT AND DESIGN 50 adult patients who suffer from COVID-19 infection, and do not participant in any other clinical trial. Patient must agree to not participate in

Colchicine Twice Daily During 10 Days as an Option for the Treatment of Symptoms Induced by Inflammation in Patients With Mild and Severe Coronavirus Disease

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This a placebo-controlled double-blind clinical trial to test the efficacy and security of colchicine 1.5 mg at day one followed by 0.5 mg BID to complete 10 days of treatment. The researchers will recruit patients 18-70 years of age who are hospitalized because of the diagnosis of mild or severe

Fecal Microbiota Transplantation as a Therapeutic Strategy in the Progression of Chronic Kidney Disease

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What the investigators want to achieve with the protocol is to identify that impact has transplantation intestinal microbiota on the progression of chronic kidney disease A.-Hypothesis: Modification of intestinal microbioma of CKD patients by TMF decrease the progression of CKD. B.-Specific

DSS's Role in Evaluating the Diagnosis and Treatment System of Ischemic Cardiovascular and Cerebrovascular Diseases

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The experiments as follows: Experiment 1. Observe the dynamic changes of DSS level in acute ischemic cardiovascular and cerebrovascular diseases of different severity. 1. Research object Acute myocardial infarction (AMI) group: 500 patients with AMI; Acute ischemic stroke group: 300 patients with

Study of Verinurad in Heart Failure With Preserved Ejection Fraction

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Evidence shows independent associations between hyperuricaemia and the risk of cardio-renal conditions, including heart failure (HF). Serum uric acid (sUA) is also a strong prognostic factor and correlates with other markers of poor prognosis in HF patients with preserved ejection fraction (HFpEF),

Constipation, Gut Microbiome, and Microbial-derived Uremic Toxins From the Gut Microbiota in HD Patients

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Study Design and Population Patients and Methods This study will include 90 dialysis patients. Patients over age 20 years old and undergoing HD for at least 6 months will be enrolled. Patients with inflammatory diseases, cancer, AIDS, autoimmune disease, use of a central catheter for hemodialysis

Effect of Camel Milk With Probiotic on Type 2 Diabetes Mellitus

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Neuroinflammation, Affective and Cognitive Symptoms in Major Depression and Psoriasis

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Design This is a prospective observational study of cohorts with patients diagnosed with major depression or psoriasis and subjected to different treatments with systemic or biological drugs in the case of psoriasis, and with antidepressants in the case of major depression. Subjects of study The

The Immune System in End Stage CKD Patients - Comparison Among Different Modalities of RRT

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The sustained inflammatory state in CKD is of complex pathogenesis and is believed to be in part attributable to the augmented activation of innate immune system cell subsets. The activation of the innate immune system plays an essential role within all the spectrum of cardiovascular disease in CKD,

Cardiac Biomarkers in Preeclampsia: Prediction of Disease and the Risk of Future Cardiovascular Events in Survivors

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Preeclampsia is a disease that is strongly linked with the risk of stroke and other cardiovascular disease. This is a condition with greater prevalence in the Low and middle income countries of the world especially sub-Saharan Africa, where the morbidity and mortality is reportedly higher. Larger

The Influence of Urate-lowering Therapy on Sperm Quality of Male Gouty Patients：A Prospective Cohort Study

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1. Research drugs. Three kinds of uric acid lowering drugs, allopurinol, febuxostat and benzbromarone, will be evaluated in this study. 2. Study design and sample size calculation. This study was designed as a single-center prospective cohort study. Age-matched sperm donors from the human sperm bank

Sickle Cell Uric Acid (SCUA) - Cohort Repository

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Sickle Cell Disease causes kidney injury over time, but it is not clear why some individuals have very significant chronic kidney disease and why some do not. The purpose of this research is to study whether having high levels of 'uric acid,' which is a naturally occurring molecule in the body that

Optimal Clinical Predictors to AKI in Cirrhotic Patients Experienced Acute Gastrointestinal Hemorrhage

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Specific aims of this study : 1. To examine the influences of acute gastrointestinal hemorrhage on the serological or urinary level of novel renal biomarkers in patients with cirrhosis. 2. To investigate the ability of novel biomarkers to predict the development of acute kidney injury and the

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Herbal & Natural Medicine

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