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Upper-body High-intensity Interval Training and Mixed Meal Responses

Тільки зареєстровані користувачі можуть перекладати статті
Увійти Зареєструватися
Посилання зберігається в буфері обміну
СтатусВербування
Спонсори
University of Bath

Ключові слова

Анотація

Cycling and running-based high-intensity interval training are well-established to improve a variety of health outcomes. However, the efficacy of upper-body high-intensity interval training, vital for individuals with lower-body impairments, has yet to be well-characterized. The purpose of this study is to compare the effect of a single bout of upper-body high-intensity interval exercise (HIIE) in comparison to traditional moderate-intensity continuous exercise (MICE) on the blood response (e.g. glucose, insulin, fats) following a meal.
This study is recruiting able-bodied adults (aged 18-65 years). Participants will need to attend the laboratory at the University of Bath for two preliminary sessions, and three main study trials.

Опис

The aim of this research is to determine the metabolic responses to a mixed-meal tolerance test following an acute bout of HIIE and an energy-matched MICE bout in able-bodied persons. The hypothesis is that HIIE and MICE will be more effective at reducing the total triglyceride responses compared to a resting control condition.

Preliminary measurements:

Preliminary testing will include measurements of weight and height. There will also be an assessment of resting metabolic rate and maximal exercise capacity. On a second visit, a HIIE familiarisation session will be performed to determine total energy expenditure of the session. All of the exercise protocols will take place on an arm crank ergometer at the University of Bath.

Main trial days:

Before all main trials, participants will be asked to refrain from performing any strenuous physical activity in the 48-h prior (i.e. day 0 and 1) and consuming alcohol/caffeine in the 24-h prior (i.e. day 1). On day 1, participants will be asked to record/replicate their diet using a weighed food-diary. Participants will be asked perform exercise (HIIE and MICE only) at 18:00 on day 1, having consumed no food (other than plain water) from 14:00. They will be given a standardised dinner to eat at 20:00, and asked to avoid the ingestion of any further food (other than plain water) for the rest of the evening.

On day 2 and upon arrival to the laboratory, a cannula will be inserted into a vein, and a baseline blood sample and expired air sample will be taken. The participant will then be asked to consume a smoothie, consisting of peanut butter, banana, coconut oil, sugar, and chocolate-flavoured whey protein powder. The meal should be consumed within 10 minutes and blood samples will be taken from the cannula at 15, 30, 45 60, and 90 minutes and then at every hour for 5 hours after consumption of the meal to monitor changes in metabolic markers. Expired gas samples will also be taken hourly and indirect calorimetry will be used to estimate relative fat and carbohydrate metabolism in response to the meal.

Дати

Востаннє перевірено: 01/31/2020
Перший поданий: 02/09/2020
Орієнтовна реєстрація подана: 02/17/2020
Опубліковано вперше: 02/19/2020
Останнє оновлення надіслано: 02/17/2020
Останнє оновлення опубліковано: 02/19/2020
Фактична дата початку навчання: 10/20/2019
Розрахункова дата первинного завершення: 04/30/2020
Розрахункова дата завершення дослідження: 04/30/2020

Стан або захворювання

High-Intensity Interval Training

Втручання / лікування

Other: High-intensity interval exercise

Other: Moderate-intensity continous exercise

Фаза

-

Групи рук

РукаВтручання / лікування
No Intervention: Control
No exercise
Experimental: High-intensity interval exercise
10 x 60 s intervals at 80% peak power output (interspersed with 60 s recovery intervals at 10% peak power output)
Other: High-intensity interval exercise
Arm-cranking exercise
Experimental: Moderate-intensity continous exercise
50% peak power output (duration determined to elicit same energy expenditure as high-intensity interval exercise condition)
Other: Moderate-intensity continous exercise
Arm-cranking exercise

Критерії прийнятності

Вік, придатний для навчання 18 Years До 18 Years
Стать, яка підходить для вивченняAll
Приймає здорових добровольцівТак
Критерії

Inclusion Criteria:

- Non-smoker

- No history of cardiovascular, metabolic, or neuromuscular disease

Exclusion Criteria:

- Individuals with a nut allergy

Результат

Заходи первинного результату

1. Postprandial triglyceride concentrations [5 hours]

Postprandial triglyceride concentrations in serum samples

Заходи вторинного результату

1. Postprandial glucose concentrations [5 hours]

Postprandial glucose concentrations in serum samples

2. Postprandial insulin concentrations [5 hours]

Postprandial insulin concentrations in serum samples

3. Postprandial substrate oxidation [5 hours]

Postprandial substrate oxidation determined by indirect calorimetry

4. Rating of Perceived Exertion [HIIE: End of Warm-Up, 8 min, 12 min, 16 min, 20 min, 24 min. MICE: 0, 20, 40, 60, 80, 100% through exercise session (exact time points dependent on exercise time for each participant)]

Global, central, and local rating of perceived exertion (6-20) during exercise

5. Heart Rate [HIIE: End of Warm-Up, 8 min, 12 min, 16 min, 20 min, 24 min. MICE: 0, 20, 40, 60, 80, 100% through exercise session (exact time points dependent on exercise time for each participant)]

Heart rate during exercise

6. Affect [HIIE: End of Warm-Up, 8 min, 12 min, 16 min, 20 min, 24 min. MICE: 0, 20, 40, 60, 80, 100% through exercise session (exact time points dependent on exercise time for each participant)]

Affect measured through the Feeling Scale (FS) during exercise. FS is a one item scale ranging from +5 ("Very good") to -5 ("Very bad").

7. Exercise Enjoyment [30 min post-exercise]

Enjoyment measured by the Physical Activity Enjoyment Scale (PACES). PACES is a 17-item scale, with each item scored from 1 to 7. The total score will be calculated.

8. Self-efficacy [30 min post-exercise]

Confidence in ability to perform exercise performed during trial in the next 4 weeks measured using a 5-item scale ranging from 0% ("Not at all" to 100% ("Extremely confident").

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