Nephrology 2020-Mar
Serum Electrolyte Dynamics in Multiple Myeloma Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation.
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RESULTS
Engraftment speed (ES) was calculated as the period between the first rise in the absolute neutrophil count (ANC) and full engraftment defined as the first of 3 consecutive days with ANC > 500 x 106 /L. The defined median engraftment speed (ES) was 2 days (range 0-5 days) and 40 patients had ES ≤2 days. Engraftment occurred at a median of 10 days. The median time-to-nadir for phosphorus and potassium was 10 days and 4.28 days, respectively. The drop in phosphorus and potassium serum level was statistically greater in patients with an ES ≤2 days compared to patients with ES ≥2 days. Magnesium level were not significantly affected and there was no significant difference between the drop in serum phosphorus and potassium based on severity of nausea or oral mucositis.