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Endometrial tubal metaplasia (ETM) is mostly described in conjunction with unopposed estrogen levels, and its association with endometrial hyperplasia and endometrial carcinoma (EC) is striking. Obesity is a risk factor for endometrial hyperplasia and EC development. The aim of this BACKGROUND
Recently, we showed that the length of cardiac mucosa in healthy volunteers correlated with age and obesity. We have now examined the immunohistological characteristics of this expanded cardia to determine whether it may be due to columnar metaplasia of the distal oesophagus.
METHODS
We
A 56-year female is described who developed recurrent oxalate nephrolithiasis six years following jejunoileal by-pass surgery for morbid obesity. Subsequently a revision of the jejunoileal by-pass was performed when it was recognized that the site of the anastomosis showed segmental dilatation
The endoscopic inaccessibility of the gastric remnant after Roux-en-Y gastric bypass (RYGBP) for morbid obesity represents an important issue for patients with familiar history of gastric cancer (GC) or affected by premalignant lesions, such as intestinal metaplasia. If a different bariatric
Gastric bypass in patients with morbid obesity should be an excellent antireflux procedure, because no acid is produced at the small gastric pouch and no duodenal reflux is present, due to the long Roux-en-Y limb. Five hundred fifty-seven patients with morbid obesity submitted to resectional gastric
OBJECTIVE
To assess the role of Helicobacter pylori (H. pylori), gastroesophageal reflux disease (GERD), age, smoking and body weight on the development of intestinal metaplasia of the gastric cardia (IMC).
METHODS
Two hundred and seventeen patients scheduled for esophagogastroduodenoscopy were
Although 10% to 15% of gastro-oesophageal reflex disease (GERD) patients have Barrett's oesophagus, neither the frequency nor the severity of symptoms correlates with the presence of Barrett's epithelium. Age, male sex, white race, and obesity have been implicated in some studies. The studies in
Vertical banded gastroplasty is an accepted surgical treatment for morbid obesity. The aim of this study was to evaluate its effect on the natural history of gastritis, as the occurrence of gastritis and dysplasia have been reported after gastric bypass, another type of bariatric surgery.
OBJECTIVE
To compare esophageal motor function in patients with reflux esophagitis with controls, and identify patient characteristics that may have a bearing on the severity of esophageal motor dysfunction and acid exposure.
METHODS
Esophageal motor function was assessed in 60 patients with reflux
A positive association between body mass index (BMI) and risk of esophageal adenocarcinoma has been reported. Barrett esophagus (BE) is a precursor lesion for esophageal adenocarcinoma. Cardiac mucosa (CM) and BE are both reflux-induced metaplastic columnar epithelia in the esophagus. We
BACKGROUND
Overweight can be a risk factor for pathological gastroesophageal reflux or hiatal hernia.
OBJECTIVE
To study the prevalence of gastroesophageal reflux in patients with severe obesity.
METHODS
Sixty seven patients, 51 female, aged 17 to 56 years old with a body mass index over 35 kg/m2,
OBJECTIVE
Earlier reports from Saudi Arabia have shown high prevalence of Helicobacter pylori infection. However, recent studies have documented a reduction in the infection prevalence. No prior study has assessed the prevalence in morbidly obese Saudi patients. We aimed to study the prevalence of
OBJECTIVE
Endoscopic evaluation of the excluded stomach after Roux-en-Y gastric bypass surgery for morbid obesity is a challenge, and the pathological changes that take place in the bypassed stomach are unclear. A new double-balloon method of evaluating the bypassed stomach after Roux-en-Y gastric
OBJECTIVE
In the West, a substantial proportion of subjects with adenocarcinoma of the gastric cardia and gastroesophageal junction have no history of reflux. We studied the gastroesophageal junction in asymptomatic volunteers with normal and large waist circumferences (WCs) to determine if central
BACKGROUND
Sleeve gastrectomy (SG) has been used as a multipurpose surgical procedure for the treatment of morbid obesity. The aim of the study was to analyze gastric morphology and histology at two different time points after SG in rats.
METHODS
Thirty-five male Wistar rats were fed ad libitum