3 результати
Data on psychological harm in multiple endocrine neoplasia type 2 (MEN2) are scarce.
The aim of this study was to assess anxiety, depression, quality of life, and coping in long-standing MEN2 patients.
Patients were 43 adults (age ≥18 years) with clinical and genetic diagnosis of MEN2 and long-term
Multiple Endocrine Neoplasia type IIa (MEN IIa) is an autosomal dominant syndrome characterized by pheochromocytoma, medullary thyroid carcinoma and hyperparathyroidism. Pheochromocytoma occurs in approximately 50% of patients with MEN IIa. This tumor has the capacity to produce ACTH ectopically and
Primary hyperparathyroidism (PHPT) is characterized by excessive PTH secretion in respect to calcium homeostasis needs, due to parathyroid adenoma (80% of cases), hyperplasia (15-20%), or carcinoma (1-2%). In familial forms of PHPT, several mutations have an established role: menin gene for MEN type