A new cytotoxic dinaphthofuran-7,12-dione derivatives from the seeds of Impatiens balsamina.
Từ khóa
trừu tượng
OBJECTIVE
To study the chemical constituents of seeds of Impatiens balsamina.
METHODS
The chemical constituents of the plant were isolated and purified by column chromatography and their structures were elucidated on the basis of physicochemical properties and spectral date.
RESULTS
A new dinaphthofuran-7,12-dione derivative, named balsaminone C(1), with another two known dinaphthofuran-7,12-dione derivatives, balsaminone A (2), balsaminone B (3) were isolated.
CONCLUSIONS
Compound 1 is a new compound. These compounds exhibit cytotoxicity against cancer cell lines A549, Bel-7402 and Hela. Compound 1 is worth to be further studied as potential anticancer agent.