Natural Product Research 2019-Jan
Four C-geranyl flavonoids from the flowers of Paulownia fortunei and their anti-inflammatory activity.
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Four new C-geranyl flavonoids, paulownione D-G (1-4) were isolated from the 50% acetone-H2O extract of the flowers of Paulownia fortunei. The structures of the compounds were determined by extensive spectroscopic analyses (UV, IR, HR-ESI-MS, 1D and 2D NMR). All of the compounds (1-4) exhibited potent protection effects in H9c2 cardiocytes against the lipopolysaccharide (LPS)-induced inflammation.