Annales de medecine interne 1999-Jun
[Opsoclonus-myoclonus syndrome in the adult. 4 cases].
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Four cases of opsoclonus in adults are reported. In all cases, it was associated with myoclonus and cerebellar syndrome. In 2 cases, the clinical and biological picture was suggestive of an infectious origin, and the patients recovered. The last cases are paraneoplastic opsoclonus revelating a pulmonary carcinoma and a breast cancer. The two patients died from metastasis after a transient improvement of ocular disorder. The pathophysiology of opsoclonus is discussed.