International Journal of Mycobacteriology 2016-Jun
Treatment of severe refractory erythema nodosum leprosum with tumor necrosis factor inhibitor Etanercept.
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Erythema nodosum leprosum (ENL) is a common complication of lepromatous leprosy. Some patients unresponsive to conventional, first-line therapeutics develop recurrent, recalcitrant ENL. Here, we report a case of severe refractory ENL that was successfully treated with Etanercept. Biologics may be considered as therapeutic alternatives in management of severe, recalcitrant ENL.